Respiratory syncytial virus (RSV) is amongst the most important pathogenic infections of
childhood and is associated with significant morbidity and mortality. Although there have …

Macrophage inflammatory protein-1α (MIP-1α) and MIP-1β are highly related members of
the CC chemokine subfamily. Despite their structural similarities, MIP-1α and MIP-1β show …

Respiratory syncytial virus (RSV) is an important etiological agent of respiratory infection in
children for which no specific treatment option is available. The RSV virion contains two …

Rhinoviruses are the major cause of the common cold and a trigger of acute asthma
exacerbations. Whether these exacerbations result from direct infection of the lower airway …

Secondary bacterial infections often complicate respiratory viral infections, but the
mechanisms whereby viruses predispose to bacterial disease are not completely …

Despite vaccines and antiviral substances influenza still causes significant morbidity and
mortality world wide. Better understanding of the molecular mechanisms of influenza virus …

The airway epithelial cell is the initial cell type impacted both by inhaled environmental
factors, such as pathogens, allergens, and pollutants, and inhaled medications for airway …

Eosinophils are recruited to the lungs in response to respiratory syncytial virus (RSV)
infection; however, their role in promoting antiviral host defense remains unclear. Here, we …

Respiratory syncytial virus (RSV) is a major cause of severe pneumonia and bronchiolitis in
infants and young children, and causes disease throughout life. Understanding the biology …

Influenza A virus causes respiratory tract infections, which are occasionally complicated by
secondary bacterial infections. Influenza A virus replicates in epithelial cells and leukocytes …