Home as the new frontier for the treatment of COVID-19: the case for anti-inflammatory agents

N Perico, M Cortinovis, F Suter… - The Lancet Infectious …, 2023 - thelancet.com
Summary COVID-19, caused by SARS-CoV-2, is characterised by a broad spectrum of
symptom severity that requires varying amounts of care according to the different stages of …

SARS coronavirus 2: from genome to infectome

M Rastogi, N Pandey, A Shukla, SK Singh - Respiratory research, 2020 - Springer
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) belongs to the group of
Betacoronaviruses. The SARS-CoV-2 is closely related to SARS-CoV-1 and probably …

[HTML][HTML] Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial

S Ramakrishnan, DV Nicolau, B Langford… - The Lancet …, 2021 - thelancet.com
Background Multiple early reports of patients admitted to hospital with COVID-19 showed
that patients with chronic respiratory disease were significantly under-represented in these …

Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive …

LM Yu, M Bafadhel, J Dorward, G Hayward, BR Saville… - The Lancet, 2021 - thelancet.com
Background A previous efficacy trial found benefit from inhaled budesonide for COVID-19 in
patients not admitted to hospital, but effectiveness in high-risk individuals is unknown. We …

Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using …

CI Bloom, TM Drake, AB Docherty… - The Lancet …, 2021 - thelancet.com
Background Studies of patients admitted to hospital with COVID-19 have found varying
mortality outcomes associated with underlying respiratory conditions and inhaled …

Risk factors for severity on admission and the disease progression during hospitalisation in a large cohort of patients with COVID-19 in Japan

M Terada, H Ohtsu, S Saito, K Hayakawa, S Tsuzuki… - BMJ open, 2021 - bmjopen.bmj.com
Objectives To investigate the risk factors contributing to severity on admission. Additionally,
risk factors of worst severity and fatality were studied. Moreover, factors were compared …

COVID-19 and corticosteroids: a narrative review

G El-Saber Batiha, AI Al-Gareeb, HM Saad… - …, 2022 - Springer
It has been reported that corticosteroid therapy was effective in the management of severe
acute respiratory syndrome (SARS) and the Middle East Respiratory Syndrome (MERS) …

Inhalation delivery for the treatment and prevention of COVID-19 infection

BB Eedara, W Alabsi, D Encinas-Basurto, R Polt… - Pharmaceutics, 2021 - mdpi.com
Coronavirus disease-2019 (COVID-19) is caused by coronavirus-2 (SARS-CoV-2) and has
produced a global pandemic. As of 22 June 2021, 178 million people have been affected …

Pediatric asthma and COVID‐19: The known, the unknown, and the controversial

EM Abrams, I Sinha, RM Fernandes… - Pediatric …, 2020 - Wiley Online Library
The novel coronavirus disease‐2019 (COVID‐19), caused by the pathogen severe acute
respiratory syndrome‐CoV‐2, is causing a global pandemic, with over 26.9 million cases …

Treatments for COVID-19: Lessons from 2020 and new therapeutic options

F Salasc, T Lahlali, E Laurent, M Rosa-Calatrava… - Current Opinion in …, 2022 - Elsevier
To face the COVID-19 pandemic, prophylactic vaccines have been developed in record
time, but vaccine coverage is still limited, accessibility is not equitable worldwide, and the …