Breast cancer

N Harbeck, F Penault-Llorca… - Nature reviews …, 2019 - mayoclinic.elsevierpure.com
Breast cancer is the most frequent malignancy in women worldwide and is curable in~ 70–
80% of patients with early-stage, non-metastatic disease. Advanced breast cancer with …

A systematic review of rehabilitation and exercise recommendations in oncology guidelines

NL Stout, D Santa Mina, KD Lyons… - CA: a cancer journal …, 2021 - Wiley Online Library
Guidelines promote high quality cancer care. Rehabilitation recommendations in oncology
guidelines have not been characterized and may provide insight to improve integration of …

Atezolizumab plus nab-paclitaxel as first-line treatment for unresectable, locally advanced or metastatic triple-negative breast cancer (IMpassion130): updated efficacy …

P Schmid, HS Rugo, S Adams, A Schneeweiss… - The lancet …, 2020 - thelancet.com
Background Immunotherapy in combination with chemotherapy has shown promising
efficacy across many different tumour types. We report the prespecified second interim …

Abemaciclib combined with endocrine therapy for the adjuvant treatment of HR+, HER2−, node-positive, high-risk, early breast cancer (monarchE)

SRD Johnston, N Harbeck, R Hegg, M Toi… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Many patients with HR+, HER2− early breast cancer (EBC) will not experience
recurrence or have distant recurrence with currently available standard therapies. However …

[HTML][HTML] Trastuzumab emtansine for residual invasive HER2-positive breast cancer

G Von Minckwitz, CS Huang, MS Mano… - … England Journal of …, 2019 - Mass Medical Soc
Background Patients who have residual invasive breast cancer after receiving neoadjuvant
chemotherapy plus human epidermal growth factor receptor 2 (HER2)–targeted therapy …

[HTML][HTML] Atezolizumab and nab-paclitaxel in advanced triple-negative breast cancer

P Schmid, S Adams, HS Rugo… - … England Journal of …, 2018 - Mass Medical Soc
Background Unresectable locally advanced or metastatic triple-negative (hormone-receptor–
negative and human epidermal growth factor receptor 2 [HER2]–negative) breast cancer is …

Personalized detection of circulating tumor DNA antedates breast cancer metastatic recurrence

RC Coombes, K Page, R Salari, RK Hastings… - Clinical Cancer …, 2019 - AACR
Purpose: Up to 30% of patients with breast cancer relapse after primary treatment. There are
no sensitive and reliable tests to monitor these patients and detect distant metastases before …

Lymph node metastasis prediction from primary breast cancer US images using deep learning

LQ Zhou, XL Wu, SY Huang, GG Wu, HR Ye, Q Wei… - Radiology, 2020 - pubs.rsna.org
Background Deep learning (DL) algorithms are gaining extensive attention for their excellent
performance in image recognition tasks. DL models can automatically make a quantitative …

Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled …

M Martin, FA Holmes, B Ejlertsen, S Delaloge… - The lancet …, 2017 - thelancet.com
Background ExteNET showed that 1 year of neratinib, an irreversible pan-HER tyrosine
kinase inhibitor, significantly improves 2-year invasive disease-free survival after …

[HTML][HTML] ESO–ESMO 4th international consensus guidelines for breast cancer in young women (BCY4)

S Paluch-Shimon, F Cardoso, AH Partridge… - Annals of …, 2020 - Elsevier
Highlights•Breast cancer in young women should be treated based on stage and biology of
disease.•Management of breast cancer in young women requires special considerations …