[HTML][HTML] Primary angle closure glaucoma: what we know and what we don't know
X Sun, Y Dai, Y Chen, DY Yu, SJ Cringle… - Progress in retinal and …, 2017 - Elsevier
Primary angle-closure glaucoma (PACG) is a common cause of blindness. Angle closure is
a fundamental pathologic process in PAGC. With the development of imaging devices for the …
a fundamental pathologic process in PAGC. With the development of imaging devices for the …
Genetics of glaucoma
JL Wiggs, LR Pasquale - Human molecular genetics, 2017 - academic.oup.com
Genetic and genomic studies, including genome-wide association studies (GWAS) have
accelerated the discovery of genes contributing to glaucoma, the leading cause of …
accelerated the discovery of genes contributing to glaucoma, the leading cause of …
Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma
Glaucoma is the leading cause of irreversible blindness globally. Despite its gravity, the
disease is frequently undiagnosed in the community. Raised intraocular pressure (IOP) is …
disease is frequently undiagnosed in the community. Raised intraocular pressure (IOP) is …
Cholinergic nervous system and glaucoma: From basic science to clinical applications
The cholinergic system has a crucial role to play in visual function. Although cholinergic
drugs have been a focus of attention as glaucoma medications for reducing eye pressure …
drugs have been a focus of attention as glaucoma medications for reducing eye pressure …
The genetic basis for adult onset glaucoma: Recent advances and future directions
Glaucoma, a diverse group of eye disorders that results in the degeneration of retinal
ganglion cells, is the world's leading cause of irreversible blindness. Apart from age and …
ganglion cells, is the world's leading cause of irreversible blindness. Apart from age and …
Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma
Intraocular pressure (IOP) is currently the sole modifiable risk factor for primary open-angle
glaucoma (POAG), one of the leading causes of blindness worldwide. Both IOP and POAG …
glaucoma (POAG), one of the leading causes of blindness worldwide. Both IOP and POAG …
[HTML][HTML] Molecular genetics of glaucoma: Subtype and ethnicity considerations
Glaucoma, the world's leading cause of irreversible blindness, is a complex disease, with
differential presentation as well as ethnic and geographic disparities. The multifactorial …
differential presentation as well as ethnic and geographic disparities. The multifactorial …
Update on the genetics of primary open-angle glaucoma
Affecting nearly 80 million individuals, glaucoma is the number one cause of irreversible
blindness in the world. This ocular disease describes a set of optic neuropathies of which …
blindness in the world. This ocular disease describes a set of optic neuropathies of which …
[HTML][HTML] Scaffolding proteins of vertebrate apical junctions: structure, functions and biophysics
Tight and adherens junctions are specialized sites of cell-cell interaction in epithelia and
endothelia, and are involved in barrier, adhesion, and signaling functions. These functions …
endothelia, and are involved in barrier, adhesion, and signaling functions. These functions …
Major review: exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology
IF Aboobakar, WM Johnson, WD Stamer… - Experimental eye …, 2017 - Elsevier
Exfoliation syndrome (XFS) is a common age-related disorder that leads to deposition of
extracellular fibrillar material throughout the body. The most recognized disease …
extracellular fibrillar material throughout the body. The most recognized disease …