The efficacy and safety of colloid resuscitation in the critically ill

CS Hartog, M Bauer, K Reinhart - Anesthesia & Analgesia, 2011 - journals.lww.com
Despite evidence from clinical studies and meta-analyses that resuscitation with colloids or
crystalloids is equally effective in critically ill patients, and despite reports from high-quality …

Identification of inflammatory mediators and their modulation by strategies for the management of the systemic inflammatory response during cardiac surgery

R Hall - Journal of Cardiothoracic and Vascular Anesthesia, 2013 - jcvaonline.com
THE SYSTEMIC INFLAMMATORY RESPONSE (man-ifested by pyrexia, leukocytosis,
tachycardia, hypotension, tissue fluid accumulation, and organ failure) is generated during …

Influence of hydroxyethyl starch (HES) 130/0.4 on hemostasis as measured by viscoelastic device analysis: a systematic review

CS Hartog, D Reuter, W Loesche, M Hofmann… - Intensive care …, 2011 - Springer
Purpose Hydroxyethyl starch solutions (HES) are plasma volume expanders which affect
hemostasis. Newer HES 130/0.4 is said to be safer. Reevaluation of published evidence is …

Randomised trials of 6% tetrastarch (hydroxyethyl starch 130/0.4 or 0.42) for severe sepsis reporting mortality: systematic review and meta-analysis

A Patel, U Waheed, SJ Brett - Intensive care medicine, 2013 - Springer
Purpose To assess the impact of 6% tetrastarch [hydroxyethyl starch (HES) 130/0.4 and
130/0.42] in severe sepsis patients. The primary outcome measure was 90-day mortality …

Hydroxyethyl starch: a review of pharmacokinetics, pharmacodynamics, current products, and potential clinical risks, benefits, and use

PA Glover, E Rudloff, R Kirby - Journal of Veterinary …, 2014 - Wiley Online Library
Objective To review and summarize the pharmacokinetics and pharmacodynamics of
hydroxyethyl starch (HES), as well as reported risks and benefits of HES infusion, and to …

The crystalloid‐colloid debate: consequences of resuscitation fluid selection in veterinary critical care

D Cazzolli, J Prittie - … of Veterinary Emergency and Critical Care, 2015 - Wiley Online Library
Objective To provide a comprehensive review of the current literature in human and
veterinary medicine evaluating the impact of resuscitation fluid choice on patient outcome …

[HTML][HTML] Hydroxyethyl starch solutions and patient harm

I Roberts, H Shakur, R Bellomo, J Bion, S Finfer, B Hunt… - The Lancet, 2018 - thelancet.com
These intravenous solutions are often used for plasma volume replacement following acute
blood loss. Evidence from high-quality, investigator-initiated clinical trials in kidney donors …

Are we close to the ideal intravenous fluid?

N MacDonald, RM Pearse - BJA: British Journal of Anaesthesia, 2017 - academic.oup.com
The approach to iv fluid therapy for hypovolaemia may significantly influence outcomes for
patients who experience a systemic inflammatory response after sepsis, trauma, or major …

In vitro evaluation of canine hemostasis following dilution with hydroxyethyl starch (130/0.4) via thromboelastometry

S Falco, B Bruno, C Maurella, C Bellino… - Journal of Veterinary …, 2012 - Wiley Online Library
Objective To assess the effects of in vitro hemodilution of canine blood with a low molecular
weight hy‐droxyethyl starch (HES 130/0.4) by means of thromboelastometry (TEM). Design …

Comparison of the in vitro effects of saline, hypertonic hydroxyethyl starch, hypertonic saline, and two forms of hydroxyethyl starch on whole blood coagulation and …

VA Wurlod, J Howard, T Francey… - Journal of Veterinary …, 2015 - Wiley Online Library
Objective To compare the in vitro effects of hypertonic solutions and colloids to saline on
coagulation in dogs. Design In vitro experimental study. Setting Veterinary teaching hospital …