[HTML][HTML] Exploring the Core Formose Cycle: Catalysis and Competition

J Kua, LP Tripoli - Life, 2024 - mdpi.com
The core autocatalytic cycle of the formose reaction may be enhanced or eroded by the
presence of simple molecules at life's origin. Utilizing quantum chemistry, we calculate the …

Evidence of Selection in Mineral Mediated Polymerization Reactions Executed in a Robotic Chemputer System

S Asche, RW Pow, HM Mehr, GJT Cooper… - …, 2024 - Wiley Online Library
It has long been thought that abiogenesis requires a process of selection and evolution at
the molecular level, but this process is hard to explore experimentally. One solution could be …

[HTML][HTML] Sulfur Analogs of the Core Formose Cycle: A Free Energy Map

J Kua, MT Peña, SN Cotter, J Leca - Life, 2024 - mdpi.com
Using computational methods, we examine if the presence of H2S can tame the unruly
formose reaction by generating a free energy map of the reaction thermodynamics and …

Assembly Theory and its Relationship with Computational Complexity

C Kempes, SI Walker, M Lachmann… - arXiv preprint arXiv …, 2024 - arxiv.org
Assembly theory (AT) quantifies selection using the assembly equation and identifies
complex objects that occur in abundance based on two measurements, assembly index and …

Combined Network and High Resolution Mass Spectrometry Analysis of the Formose Reaction Reveals Mechanisms for Emergent Behaviors

R Cruz-Simbron, S Sharma, A Arya, J Ray, A Lozano… - 2024 - chemrxiv.org
The formose reaction (FR) autocatalytically converts simple plausibly prebiotic feedstocks
into molecules of biological interest, including ribose. Autocatalysis is a hallmark of life, thus …

Geothermal microfluidic systems foster prebiotic chemistry

T Matreux - 2024 - edoc.ub.uni-muenchen.de
Leben ist ein Phänomen fern vom thermodynamischen Gleichgewicht, und auch seine
Entstehung wurde vermutlich entscheidend von den vor etwa 4 Milliarden Jahren …

Abiotic Aldol Reactions of Formaldehyde with Ketoses and Aldoses–Implications for the Prebiotic Synthesis of Sugars by the Formose Reaction

SS Sutton, S Pulletikurti, H Lin, R Krishnamurthy… - Available at SSRN … - papers.ssrn.com
The aldol reactions of formaldehyde is the essence of the formose reaction, the preeminent
prebiotic pathway for accessing sugars on the early Earth. However, it is quite complex …