Recent advances in biological sample preparation methods coupled with chromatography, spectrometry and electrochemistry analysis techniques

Z Niu, W Zhang, C Yu, J Zhang, Y Wen - TrAC Trends in Analytical …, 2018 - Elsevier
Biological samples are complex and often contain many proteins, lipids and other
contaminants, which affect the separation and ionization properties of the analytes …

The n-3 docosapentaenoic acid (DPA): A new player in the n-3 long chain polyunsaturated fatty acid family

G Drouin, V Rioux, P Legrand - Biochimie, 2019 - Elsevier
The n-3 docosapentaenoic acid (n-3 DPA) is less studied n-3 long-chain polyunsaturated
fatty acid (LCPUFA), compared to its counterparts eicosapentaenoic acid (EPA) and …

Isoprostanes, neuroprostanes and phytoprostanes: An overview of 25 years of research in chemistry and biology

JM Galano, YY Lee, C Oger, C Vigor… - Progress in lipid …, 2017 - Elsevier
Since the beginning of the 1990's diverse types of metabolites originating from
polyunsaturated fatty acids, formed under autooxidative conditions were discovered. Known …

The impact of severe COVID-19 on plasma antioxidants

N Žarković, A Jastrząb, I Jarocka-Karpowicz… - Molecules, 2022 - mdpi.com
Several studies suggested the association of COVID-19 with systemic oxidative stress, in
particular with lipid peroxidation and vascular stress. Therefore, this study aimed to evaluate …

MS-based targeted metabolomics of eicosanoids and other oxylipins: Analytical and inter-individual variabilities

C Gladine, AI Ostermann, JW Newman… - Free Radical Biology and …, 2019 - Elsevier
Oxylipins, including the well-known eicosanoids, are potent lipid mediators involved in
numerous physiological and pathological processes. Therefore, their quantitative profiling …

Moving forward with isoprostanes, neuroprostanes and phytoprostanes: where are we now?

OS Ahmed, JM Galano, T Pavlickova… - Essays in …, 2020 - portlandpress.com
Polyunsaturated fatty acids (PUFAs) are essential components in eukaryotic cell membrane.
They take part in the regulation of cell signalling pathways and act as precursors in …

Development of an LC-ESI (-)-MS/MS method for the simultaneous quantification of 35 isoprostanes and isofurans derived from the major n3-and n6-PUFAs

KM Rund, AI Ostermann, L Kutzner, JM Galano… - Analytica chimica …, 2018 - Elsevier
Misregulation of oxidative and antioxidative processes in the organism–oxidative stress–
contributes to the pathogenesis of different diseases, eg inflammatory or neurodegenerative …

Impacts of oxidants and antioxidants on the emergence and progression of Alzheimer's disease

H Goshtasbi, PS Pakchin, A Movafeghi, J Barar… - Neurochemistry …, 2022 - Elsevier
The brain shows a high sensitivity to oxidative stress (OS). Thus, the maintenance and
homeostasis of the brain, in particular neural cells, regarding the reduction-oxidation (redox) …

Plant and algal lipidomes: Analysis, composition, and their societal significance

J Jouhet, E Alves, Y Boutté, S Darnet… - Progress in Lipid …, 2024 - Elsevier
Plants and algae play a crucial role in the earth's ecosystems. Through photosynthesis they
convert light energy into chemical energy, capture CO2 and produce oxygen and energy …

From MS/MS library implementation to molecular networks: Exploring oxylipin diversity with NEO-MSMS

A Elloumi, L Mas-Normand, J Bride, G Reversat… - Scientific Data, 2024 - nature.com
Oxylipins, small polar molecules derived from the peroxidation of polyunsaturated fatty acids
(PUFAs), serve as biomarkers for many diseases and play crucial roles in human physiology …