The human genome contains over one million short tandem repeats. Expansion of a subset
of these repeat tracts underlies over fifty human disorders, including common genetic …

Stress granules (SGs) are cytosolic biomolecular condensates that form in response to
cellular stress. Weak, multivalent interactions between their protein and RNA constituents …

Mutations causing amyotrophic lateral sclerosis (ALS) often affect the condensation
properties of RNA-binding proteins (RBPs). However, the role of RBP condensation in the …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Cell signaling mechanisms modulate gene expression in response to internal and external
stimuli. Cellular adaptation requires a precise and coordinated regulation of the transcription …

Biomolecular condensates, formed through phase separation, are upending our
understanding in much of molecular, cell, and developmental biology. There is an urgent …

Interaction of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) with specific single‐
stranded RNA and its relation to liquid‐liquid phase separation (LLPS) were studied in vitro …

Germinal centers (GCs) are essential for the establishment of long-lasting antibody
responses. GC B cells rely on post-transcriptional RNA mechanisms to translate activation …

Condensates are biomolecular assemblies that concentrate biomolecules without the help
of membranes. They are morphologically highly versatile and may emerge via distinct …

Liquid–liquid phase separation results in the formation of dynamic biomolecular
condensates, also known as membrane-less organelles, that allow for the assembly of …