Tetrazoles via multicomponent reactions

CG Neochoritis, T Zhao, A Domling - Chemical reviews, 2019 - ACS Publications
Tetrazole derivatives are a prime class of heterocycles, very important to medicinal
chemistry and drug design due to not only their bioisosterism to carboxylic acid and amide …

The Groebke‐Blackburn‐Bienaymé Reaction

A Boltjes, A Dömling - European Journal of Organic Chemistry, 2019 - Wiley Online Library
Imidazo [1, 2‐a] pyridine is a well‐known scaffold in many marketed drugs, such as
Zolpidem, Minodronic acid, Miroprofen and DS‐1 and it also serves as a broadly applied …

Recent Advances in the Synthesis of Imidazo[1,2‐a]pyridines: A Brief Review

J Panda, BP Raiguru, M Mishra, S Mohapatra… - …, 2022 - Wiley Online Library
This review focuses on providing comprehensive highlights of the recent synthetic pathways
of imidazo [1, 2‐a] pyridines, assisted through transition metal‐catalyzed reactions, multi …

Access to molecular complexity. Multicomponent reactions involving five or more components

VG Nenajdenko - Russian Chemical Reviews, 2020 - iopscience.iop.org
The evaluation of the significance of a chemical transformation addresses many factors,
including such important characteristics as the number of chemical bonds formed in one …

One‐Pot Construction of Bis‐Heterocycles through Isocyanide Based Multicomponent Reactions

S Ishwar Bhat - ChemistrySelect, 2020 - Wiley Online Library
Bis‐heterocycles (BHCs) are hybrid molecules comprising two linked, bound, spacer, or
fused heterocyclic skeletons. In recent years, these compounds have attracted increased …

Recent advances in the chemistry of 2-chloroquinoline-3-carbaldehyde and related analogs

WS Hamama, ME Ibrahim, AA Gooda, HH Zoorob - RSC advances, 2018 - pubs.rsc.org
This review highlights the recently cited research data in the literature on the chemistry of 2-
chloroquinoline-3-carbaldehyde and related analogs and their applications over the period …

Solvent- and Catalyst-Free One-Pot Green Bound-Type Fused Bis-Heterocycles Synthesis via Groebke–Blackburn–Bienaymé Reaction/SNAr/Ring-Chain Azido …

MA Claudio-Catalán, SG Pharande… - ACS …, 2018 - ACS Publications
A new, efficient, green, endogenous water-triggered, solvent-and catalyst-free ultrasound-
assisted one-pot Groebke–Blackburn–Bienaymé reaction/SNAr/ring-chain azido …

Endogenous water-triggered and ultrasound accelerated synthesis of 1, 5-disubstituted tetrazoles via a solvent and catalyst-free Ugi-azide reaction

SG Pharande, ARC Escobosa, R Gámez-Montaño - Green Chemistry, 2017 - pubs.rsc.org
Endogenous water-triggered and ultrasound accelerated synthesis of 1,5-disubstituted tetrazoles
via a solvent and catalyst-free Ugi-azide reaction - Green Chemistry (RSC Publishing) …

Ultrasound assisted green synthesis of bound type bis-heterocyclic carbazolyl imidazo [1, 2-a] pyridines via Groebke-Blackburn-Bienayme reaction

M Kurva, SG Pharande, A Quezada-Soto… - Tetrahedron …, 2018 - Elsevier
A series of seventeen novel 3-imidazo [1, 2-a] pyridine carbazoles bound type bis-
heterocycles were synthesized by Ultrasound irradiation (USI) assisted Groebke-Blackburn …

Exploration of Synthetic Potential of Quinoline‐3‐Carbaldehydes

V Kumar, S Sharma, Vaishali, D Singh… - European Journal of …, 2024 - Wiley Online Library
Quinoline is one of the most important nitrogen containing heterocycles, being widespread
in nature and present in a broad variety of pharmacologically active compounds …