Pathogenesis of Helicobacter pylori Infection

JG Kusters, AHM Van Vliet… - Clinical microbiology …, 2006 - Am Soc Microbiol
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Nickel homeostasis and nickel regulation: an overview

Y Li, DB Zamble - Chemical reviews, 2009 - ACS Publications
Nickel is an essential catalytic cofactor of enzymes found in eubacteria, archaebacteria,
fungi, and plants. 1-6 These enzymes catalyze a diverse array of reactions that include both …

Helicobacter pylori moves through mucus by reducing mucin viscoelasticity

JP Celli, BS Turner, NH Afdhal… - Proceedings of the …, 2009 - National Acad Sciences
The ulcer-causing gastric pathogen Helicobacter pylori is the only bacterium known to
colonize the harsh acidic environment of the human stomach. H. pylori survives in acidic …

Non-classical protein secretion in bacteria

JD Bendtsen, L Kiemer, A Fausbøll, S Brunak - BMC microbiology, 2005 - Springer
Background We present an overview of bacterial non-classical secretion and a prediction
method for identification of proteins following signal peptide independent secretion …

GroEL of Lactobacillus johnsonii La1 (NCC 533) Is Cell Surface Associated: Potential Role in Interactions with the Host and the Gastric Pathogen Helicobacter pylori

GE Bergonzelli, D Granato, RD Pridmore… - Infection and …, 2006 - Am Soc Microbiol
Heat shock proteins of the GroEL or Hsp60 class are highly conserved proteins essential to
all living organisms. Even though GroEL proteins are classically considered intracellular …

Release of Helicobacter pylori vacuolating cytotoxin by both a specific secretion pathway and budding of outer membrane vesicles. Uptake of released toxin and …

R Fiocca, V Necchi, P Sommi, V Ricci… - The Journal of …, 1999 - Wiley Online Library
The mechanisms by which Helicobacter pylori releases its virulence factors are poorly
known. Active secretion has been proposed for some products, including a vacuolating toxin …

GroEL (Hsp60) of Clostridium difficile is involved in cell adherence

C Hennequin, F Porcheray… - …, 2001 - microbiologyresearch.org
Previous results have demonstrated that adherence of Clostridium difficile to tissue culture
cells is augmented by various stresses; this study focussed on whether the GroEL heat …

Phosphorylation of tyrosine 972 of the Helicobacter pylori CagA protein is essential for induction of a scattering phenotype in gastric epithelial cells

S Backert, S Moese, M Selbach… - Molecular …, 2001 - Wiley Online Library
Helicobacter pylori colonizes the human stomach and is the causative agent of a variety of
gastric diseases. After bacterial attachment, the H. pylori CagA protein is translocated into …

Mechanisms of acid resistance due to the urease system of Helicobacter pylori

DR Scott, EA Marcus, DL Weeks, G Sachs - Gastroenterology, 2002 - Elsevier
Background & Aims: Helicobacter pylori, a neutralophile, uses acid neutralization by urease
to combat gastric acidity, allowing gastric colonization. Both acute and chronic acid …

Proteome Analysis of Secreted Proteins of the Gastric Pathogen Helicobacter pylori

D Bumann, S Aksu, M Wendland, K Janek… - Infection and …, 2002 - Am Soc Microbiol
Secreted proteins (the secretome) of the human pathogen Helicobacter pylori may mediate
important pathogen-host interactions, but such proteins are technically difficult to analyze …