Novel targets to arrest neurodegeneration in several dementing conditions involving
misfolded protein accumulations may be found in the diverse signaling pathways of the …

While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …

Alzheimer's disease (AD) is a complex neurodegenerative disease in the elderly and the
most common cause of human dementia. AD is characterized by accumulation of abnormal …

Neurodegenerative disorders of ageing (NDAs) such as Alzheimer disease, Parkinson
disease, frontotemporal dementia, Huntington disease and amyotrophic lateral sclerosis …

Autophagy is central to the maintenance of organismal homeostasis in both physiological
and pathological situations. Accordingly, alterations in autophagy have been linked to …

Adenosine monophosphate-activated protein kinase (AMPK) is a key metabolic sensor that
is pivotal for the maintenance of cellular energy homeostasis. AMPK contributes to diverse …

Alzheimer's disease (AD) is a progressive and neurodegenerative disorder of the cortex and
hippocampus, which eventually leads to cognitive impairment. Although the etiology of AD …

Alzheimer's disease (AD), due to its spread, has become a global health priority, and is
characterized by senile dementia and progressive disability. The main cause of AD and …

Alzheimer's disease (AD) is the most common cause of progressive dementia in the elderly.
It is characterized by a progressive and irreversible loss of cognitive abilities and formation …

Disruption of autophagy plays an import role in neurodegenerative disorders, where
deficient elimination of abnormal and toxic protein aggregates promotes cellular stress …