Prediction of aerosol deposition in the human respiratory tract via computational models: A review with recent updates

VKH Bui, JY Moon, M Chae, D Park, YC Lee - Atmosphere, 2020 - mdpi.com
The measurement of deposited aerosol particles in the respiratory tract via in vivo and in
vitro approaches is difficult due to those approaches' many limitations. In order to overcome …

In silico approaches to respiratory nasal flows: A review

K Inthavong, P Das, N Singh, J Sznitman - Journal of biomechanics, 2019 - Elsevier
The engineering discipline of in silico fluid dynamics delivers quantitative information on
airflow behaviour in the nasal regions with unprecedented detail, often beyond the reach of …

A porous circulation model of the human brain for in silico clinical trials in ischaemic stroke

TI Józsa, RM Padmos, N Samuels… - Interface …, 2021 - royalsocietypublishing.org
The advancement of ischaemic stroke treatment relies on resource-intensive experiments
and clinical trials. In order to improve ischaemic stroke treatments, such as thrombolysis and …

Analysis of flow field and turbulence predictions in a lung model applying RANS and implications for particle deposition

M Sommerfeld, OL Sgrott Jr, MA Taborda… - European Journal of …, 2021 - Elsevier
Airflow and aerosol deposition in the human airways are important aspects for applications
such as pulmonary drug delivery and human exposure to aerosol pollutants. Numerical …

Geometry and airflow dynamics analysis in the nasal cavity during inhalation

K Inthavong, J Ma, Y Shang, J Dong, ASR Chetty… - Clinical …, 2019 - Elsevier
Background A major issue among computational respiratory studies is the wide variety of
nasal morphologies being studied, caused by both inter-population and inter-subject …

Large-eddy simulations of the vortex-induced vibration of a low mass ratio two-degree-of-freedom circular cylinder at subcritical Reynolds numbers

D Pastrana, JC Cajas, O Lehmkuhl, I Rodríguez… - Computers & …, 2018 - Elsevier
The vortex induced vibration phenomenon of a low mass ratio (m*= 2.6) two-degree-of-
freedom circular cylinder at subcritical Reynolds numbers (R e= 3900, 5300, 11,000) has …

Examining mesh independence for flow dynamics in the human nasal cavity

K Inthavong, A Chetty, Y Shang, J Tu - Computers in Biology and Medicine, 2018 - Elsevier
Increased computational resources provide new opportunities to explore sophisticated
respiratory modelling. A survey of recent publications showed a steady increase in the …

Performance and energy consumption of HPC workloads on a cluster based on Arm ThunderX2 CPU

F Mantovani, M Garcia-Gasulla, J Gracia… - Future generation …, 2020 - Elsevier
In this paper, we analyze the performance and energy consumption of an Arm-based high-
performance computing (HPC) system developed within the European project Mont-Blanc 3 …

Nasal sprayed particle deposition in a human nasal cavity under different inhalation conditions

H Calmet, K Inthavong, B Eguzkitza, O Lehmkuhl… - PloS one, 2019 - journals.plos.org
Deposition of polydisperse particles representing nasal spray application in a human nasal
cavity was performed under transient breathing profiles of sniffing, constant flow, and breath …

Pressure distribution and flow dynamics in a nasal airway using a scale resolving simulation

J Van Strien, K Shrestha, S Gabriel, P Lappas… - Physics of …, 2021 - pubs.aip.org
Airflow through the nasal cavity exhibits a wide variety of fluid dynamic behaviors due to the
intricacy of the nasal geometry. The flow is naturally unsteady and perhaps turbulent …