Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging
role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D) …

Mitochondria are the powerhouses of the cell and are involved in essential functions of the
cell, including ATP production, intracellular Ca 2+ regulation, reactive oxygen species …

Exercise training positively affects metabolic health through increased mitochondrial
oxidative capacity and improved glucose regulation and is the first line of treatment in …

Type 2 diabetes mellitus (T2DM) is an expanding global health problem, closely linked to
the epidemic of obesity. Individuals with T2DM are at high risk for both microvascular …

Type 2 diabetes mellitus (T2DM) is a systemic disease characterized by hyperglycemia,
hyperlipidemia, and organismic insulin resistance. This pathological shift in both circulating …

A sedentary lifestyle has been linked to a number of metabolic disorders that have been
associated with sub-optimal mitochondrial characteristics and an increased risk of …

The term sarcopenia refers to the loss of muscle mass that occurs with ageing. On the basis
of study results showing that muscle mass is only moderately related to functional outcomes …

Metabolic pathways involved in lactate metabolism are important to understand the
physiological response to exercise and the pathogenesis of prevalent diseases such as …

Skeletal muscle possesses dramatic metabolic plasticity that allows for the rapid adaptation
in cellular energy transduction to meet the demands of the organism. Obesity elicits changes …

Aims/hypothesis Time-restricted eating (TRE) is suggested to improve metabolic health by
limiting food intake to a defined time window, thereby prolonging the overnight fast. This …