[HTML][HTML] p53 modulation of autophagy signaling in cancer therapies: perspectives mechanism and therapeutic targets
MA Rahman, MN Park, MDH Rahman… - Frontiers in cell and …, 2022 - frontiersin.org
The key tumor suppressor protein p53, additionally known as p53, represents an attractive
target for the development and management of anti-cancer therapies. p53 has been …
target for the development and management of anti-cancer therapies. p53 has been …
[HTML][HTML] Identification of ferroptosis-related genes as potential diagnostic biomarkers for diabetic nephropathy based on bioinformatics
B Guo, M Li, P Wu, Y Chen - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Objective: This study investigated to probe ferroptosis-related diagnostic biomarkers and
underlying molecular mechanisms in Diabetic nephropathy (DN). Methods: GSE30122 and …
underlying molecular mechanisms in Diabetic nephropathy (DN). Methods: GSE30122 and …
[HTML][HTML] Molecular targets and mechanisms of Jiawei Jiaotai Pill on diabetic cardiomyopathy based on network pharmacology
YJ Wang, YL Wang, XF Jiang, JE Li - World Journal of Diabetes, 2023 - ncbi.nlm.nih.gov
BACKGROUND Jiawei Jiaotai Pill is commonly used in clinical practice to reduce apoptosis,
increase insulin secretion, and improve blood glucose tolerance. However, its mechanism of …
increase insulin secretion, and improve blood glucose tolerance. However, its mechanism of …
[HTML][HTML] Gypenoside, the Main Active Compound of Gynostemma pentaphyllum, Mitigates the Diabetic Nephropathy through Down-regulating mTOR
C Chen, D Fu, Y Wu, C Huang, P Huang - … Complementary Medicine and …, 2023 - Elsevier
Background Diabetic nephropathy (DN), as a complication of diabetes, is featured with
hypertension, hyperglycemia, proteinuria and edema. Gypenoside (GP), the main active …
hypertension, hyperglycemia, proteinuria and edema. Gypenoside (GP), the main active …
[HTML][HTML] Association of p53 codon 72 polymorphism with weight and metabolic diseases in a Central Indian population
J Abraham, D Mahapatra, P Agrawal… - Egyptian Journal of …, 2024 - Springer
Background Metabolic dysregulation leading to diabetes is a major public health concern in
India. While evidence has pointed to a role for genetic factors, there is still limited knowledge …
India. While evidence has pointed to a role for genetic factors, there is still limited knowledge …
Bioinformatics Analysis of next generation sequencing data for Risk Prediction in Patients with Type 1 diabetes mellitus
B Vastrad, C Vastrad - bioRxiv, 2022 - biorxiv.org
Type 1 diabetes mellitus (T1DM) comprise the most common forms of autoimmune disease.
The aim of this investigation was to apply a bioinformatics approach to reveal related …
The aim of this investigation was to apply a bioinformatics approach to reveal related …
TP53 Arg72Pro polymorphism and its relationship with major depressive disorder: Polimorfismo TP53 Arg72Pro e sua relação com o transtorno depressivo maior
GO Rodrigues, LSS Bonasser, M de Lima Santos… - Concilium, 2024 - clium.org
This study investigates the association between the TP53 Arg72Pro polymorphism and
major depressive disorder (MDD) using a case-control approach. The study sample …
major depressive disorder (MDD) using a case-control approach. The study sample …