An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin
K Ziqubu, PV Dludla, SXH Mthembu… - Frontiers in …, 2023 - frontiersin.org
Brown adipose tissue (BAT), a thermoregulatory organ known to promote energy
expenditure, has been extensively studied as a potential avenue to combat obesity …
expenditure, has been extensively studied as a potential avenue to combat obesity …
The role of brown adipose tissue and energy metabolism in mammalian thermoregulation during the perinatal period
C Bienboire-Frosini, D Wang, M Marcet-Rius… - Animals, 2023 - mdpi.com
Simple Summary Brown adipose tissue (BAT) is a thermogenic tissue that greatly
contributes to preventing neonatal hypothermia by activating biochemical and endocrine …
contributes to preventing neonatal hypothermia by activating biochemical and endocrine …
Triglyceride cycling enables modification of stored fatty acids
K Wunderling, J Zurkovic, F Zink, L Kuerschner… - Nature …, 2023 - nature.com
Triglyceride cycling is the process of continuous degradation and re-synthesis of triglyceride
in cellular stores. We show in 3T3-L1 adipocytes that triglycerides are subject to rapid …
in cellular stores. We show in 3T3-L1 adipocytes that triglycerides are subject to rapid …
Parallel control of cold-triggered adipocyte thermogenesis by UCP1 and CKB
JF Rahbani, J Bunk, D Lagarde, B Samborska… - Cell metabolism, 2024 - cell.com
Summary That uncoupling protein 1 (UCP1) is the sole mediator of adipocyte thermogenesis
is a conventional viewpoint that has primarily been inferred from the attenuation of the …
is a conventional viewpoint that has primarily been inferred from the attenuation of the …
Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes
Adipose tissue can recruit catabolic adipocytes that utilize chemical energy to dissipate heat.
This process occurs either by uncoupled respiration through uncoupling protein 1 (UCP1) or …
This process occurs either by uncoupled respiration through uncoupling protein 1 (UCP1) or …
[HTML][HTML] Adipose tissue and metabolic health
SM An, SH Cho, JC Yoon - Diabetes & Metabolism Journal, 2023 - synapse.koreamed.org
In this review, we provide a brief synopsis of the connections between adipose tissue and
metabolic health and highlight some recent developments in understanding and exploiting …
metabolic health and highlight some recent developments in understanding and exploiting …
Atherosclerosis, diabetes mellitus, and cancer: common epidemiology, shared mechanisms, and future management
V Katsi, I Papakonstantinou, K Tsioufis - International Journal of …, 2023 - mdpi.com
The involvement of cardiovascular disease in cancer onset and development represents a
contemporary interest in basic science. It has been recognized, from the most recent …
contemporary interest in basic science. It has been recognized, from the most recent …
Basal re-esterification finetunes mitochondrial fatty acid utilization
Objective Emerging evidence suggest the existence of constant basal lipolysis and re-
esterification of a substantial fraction of thus liberated fatty acids. In stimulated lipolysis, the …
esterification of a substantial fraction of thus liberated fatty acids. In stimulated lipolysis, the …
Futile cycles: Emerging utility from apparent futility
AK Sharma, R Khandelwal, C Wolfrum - Cell Metabolism, 2024 - cell.com
Futile cycles are biological phenomena where two opposing biochemical reactions run
simultaneously, resulting in a net energy loss without appreciable productivity. Such a state …
simultaneously, resulting in a net energy loss without appreciable productivity. Such a state …
Futile lipid cycling: from biochemistry to physiology
AK Sharma, R Khandelwal, C Wolfrum - Nature Metabolism, 2024 - nature.com
In the healthy state, the fat stored in our body isn't just inert. Rather, it is dynamically
mobilized to maintain an adequate concentration of fatty acids (FAs) in our bloodstream. Our …
mobilized to maintain an adequate concentration of fatty acids (FAs) in our bloodstream. Our …