Successful regeneration of weight‐bearing bone defects and critical‐sized cartilage defects
remains a major challenge in clinical orthopedics. In the past decades, biodegradable …

Large, elastic arteries are composed of cells and a specialized extracellular matrix that
provides reversible elasticity and strength. Elastin is the matrix protein responsible for this …

Of all biologic matrices, decellularized extracellular matrix (dECM) has emerged as a
promising tool used either alone or when combined with other biologics in the fields of tissue …

BACKGROUND Vascular replacement and repair for the treatment of atherosclerotic
disease, infection, and traumatic injury are some of the most commonly performed surgical …

Current clinical treatment strategies for the bypassing of small diameter (< 6 mm) blood
vessels in the management of cardiovascular disease frequently fail due to a lack of suitable …

From microscaled capillaries to millimeter‐sized vessels, human vasculature spans multiple
scales and cell types. The convergence of bioengineering, materials science, and stem cell …

There is a persistent and growing clinical need for readily-available substitutes for heart
valves and small-diameter blood vessels. In situ tissue engineering is emerging as a …

Williams syndrome (WS) is a relatively rare microdeletion disorder that occurs in as many as
1: 7,500 individuals. WS arises due to the mispairing of low-copy DNA repetitive elements at …

Abstract 3D bioprinting is an emerging additive manufacturing technique to fabricate
constructs for human disease modeling. However, current cell‐laden bioinks lack sufficient …

Most biomedical and pharmaceutical research of the human vascular system aims to
unravel the complex mechanisms that drive disease progression from molecular to organ …