Medicinal attributes of 1, 2, 3-triazoles: Current developments

D Dheer, V Singh, R Shankar - Bioorganic Chemistry, 2017 - Elsevier
Triazoles are important five-membered heterocyclic scaffold due to their extensive biological
activities. This framework can be readily obtained in good to excellent yields on the …

Antibacterial activities with the structure-activity relationship of coumarin derivatives

HL Qin, ZW Zhang, L Ravindar, KP Rakesh - European journal of medicinal …, 2020 - Elsevier
The development of drug-resistant bacteria, as well as multidrug-resistant pathogens related
to substantial mortality, is an important global health threat. The wide range of biological …

Comprehensive review on the anti-bacterial activity of 1, 2, 3-triazole hybrids

B Zhang - European Journal of Medicinal Chemistry, 2019 - Elsevier
Bacterial infections, caused predominately by Gram-positive and Gram-negative organisms,
are proliferation of harmful strains of bacteria on or inside the body. Hospital-acquired and …

Seeking heterocyclic scaffolds as antivirals against dengue virus

S De, B Aamna, R Sahu, S Parida, SK Behera… - European Journal of …, 2022 - Elsevier
Dengue is one of the most typical viral infection categorized in the Neglected Tropical
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …

Coumarin‐containing hybrids and their antibacterial activities

D Feng, A Zhang, Y Yang, P Yang - Archiv der Pharmazie, 2020 - Wiley Online Library
Infections caused by Gram‐positive and‐negative bacteria are one of the foremost causes of
morbidity and mortality globally. Antibiotics are the mainstay of therapy for bacterial …

A recent overview of 1, 2, 3‐triazole‐containing hybrids as novel antifungal agents: Focusing on synthesis, mechanism of action, and structure‐activity relationship …

M Marzi, M Farjam, Z Kazeminejad… - Journal of …, 2022 - Wiley Online Library
A pharmacophore system has been found as 1, 2, 3‐triazole, a five‐membered heterocycle
ring with nitrogen heteroatoms. These heterocyclic compounds can be produced using …

Design, synthesis, characterization, antimicrobial evaluation and molecular modeling studies of some dehydroacetic acid-chalcone-1, 2, 3-triazole hybrids

K Lal, P Yadav, A Kumar, A Kumar, AK Paul - Bioorganic chemistry, 2018 - Elsevier
A series of new dehydroacetic acid chalcone-1, 2, 3-triazole hybrids as potential
antimicrobial agents was designed, synthesized and characterized by FTIR, NMR and …

Synthesis and biological properties of coumarin derivatives. A review

A Bouhaoui, M Eddahmi, M Dib, M Khouili… - …, 2021 - Wiley Online Library
Coumarin and its derivatives are widely used as scaffolds in the synthesis of new
heterocyclic systems. This review focuses on current developments in the synthesis of …

Molecular insights into coumarin analogues as antimicrobial agents: Recent developments in drug discovery

RS Cheke, HM Patel, VM Patil, IA Ansari, JP Ambhore… - Antibiotics, 2022 - mdpi.com
Simple Summary Coumarins are a large family of benzopyrones, and more than 1300
coumarins have been reported to date. Natural, as well as synthetic, coumarins have …

Synthesis, antimalarial and antioxidant activity of coumarin appended 1, 4-disubstituted 1, 2, 3-triazoles

CP Kaushik, M Chahal - Monatshefte für Chemie-Chemical Monthly, 2021 - Springer
A series of coumarin appended triazole hybrids of biotic interest was synthesized through
click chemistry approach from the coumarin based terminal alkynes and aromatic azides. All …