Oxidative stress signaling in the pathogenesis of diabetic cardiomyopathy and the potential therapeutic role of antioxidant naringenin

N Xu, S Liu, Y Zhang, Y Chen, Y Zuo, X Tan, B Liao… - Redox …, 2023 - Taylor & Francis
Diabetes mellitus (DM) is one of the most prevalent metabolic disorders that poses a global
threat to human health. It can lead to complications in multiple organs and tissues, owing to …

[HTML][HTML] Organ-differential roles of Akt/FoxOs axis as a key metabolic modulator during aging

DH Kim, EJ Bang, S Ha, HJ Jung, YJ Choi… - Aging and …, 2021 - ncbi.nlm.nih.gov
FoxOs and their post-translational modification by phosphorylation, acetylation, and
methylation can affect epigenetic modifications and promote the expression of downstream …

Integrative analysis of miRNA and mRNA expression associated with the immune response in the intestine of rainbow trout (Oncorhynchus mykiss) infected with …

L Zhao, J Huang, S Wu, Y Li, Y Pan - Fish & Shellfish Immunology, 2022 - Elsevier
Rainbow trout (Oncorhynchus mykiss), an economically important cold-water fish cultured
worldwide, suffers from infectious hematopoietic necrosis virus (IHNV) infection, resulting in …

Cannabidiol ameliorates inflammatory response partly by AGE‐RAGE pathway in diabetic mice

S Li, C Fan, X Li, S Li, T Yu, W Zhang… - Drug Development …, 2023 - Wiley Online Library
Cannabidiol (CBD), the most abundant nonpsychoactive constituent of Cannabis sativa
plant, is a promising potential pharmacotherapy for the treatment of diabetes and associated …

Lycopene in Combination with Insulin Triggers Antioxidant Defenses and Increases the Expression of Components That Detoxify Advanced Glycation Products in …

ID Figueiredo, TFO Lima, PF Carlstrom, RP Assis… - Nutrients, 2024 - mdpi.com
Background: Biochemical events provoked by oxidative stress and advanced glycation may
be inhibited by combining natural bioactives with classic therapeutic agents, which arise as …

The effect of a methylxanthine vasodilator: pentoxifylline on the treatment of diabetic nephropathy—a meta-analysis

M Zhang, Y Wang, W Fu, L Sun - Naunyn-Schmiedeberg's Archives of …, 2024 - Springer
This meta-analysis aimed to comprehensively evaluate the efficacy and safety of
pentoxifylline (PTF) in the treatment of diabetic nephropathy (DN) and to offer fresh …

A randomized double-blinded placebo-controlled clinical trial on protective effects of pentoxifylline on gentamicin nephrotoxicity in infectious patients

SR Mousavinasab, Z Akhoundi-Meybodi… - Clinical and …, 2021 - Springer
Background and objective Renal toxicity has limited gentamicin use in clinical practice. The
aim of the present clinical trial was to assess the possible nephroprotective effects of …

Brief research report: Repurposing pentoxifylline to treat intense acute swimming–Induced delayed-onset muscle soreness in mice: Targeting peripheral and spinal …

SM Borghi, TH Zaninelli, T Saraiva-Santos… - Frontiers in …, 2023 - frontiersin.org
In this study, we pursue determining the effect of pentoxifylline (Ptx) in delayed-onset muscle
soreness (DOMS) triggered by exposing untrained mice to intense acute swimming exercise …

[HTML][HTML] 痰瘀同治法对糖尿病大鼠心肌微血管病变AGEs/RAGE 轴及氧化应激的影响

许笑雯, 储全根, 储俊, 蔡正银, 轩云… - Journal of Southern …, 2021 - ncbi.nlm.nih.gov
痰瘀同治法对糖尿病大鼠心肌微血管病变AGEs/RAGE轴及氧化应激的影响- PMC Back to Top
Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …

Effect of dissipating phlegm and blood stasis simultaneously on ages/rage axis and oxidative stress in rats with diabetic myocardial microangiopathy

X Xu, Q Chu, J Chu, Z Cai, Y Xuan, B Luo… - … Fang yi ke da xue xue …, 2021 - europepmc.org
Objective To investigate the effect of dissipating phlegm and blood stasis simultaneously for
protecting cardiac microvascular endothelial cells (CMECs) against high glucose-induced …