Materials design for bone-tissue engineering

GL Koons, M Diba, AG Mikos - Nature Reviews Materials, 2020 - nature.com
Successful materials design for bone-tissue engineering requires an understanding of the
composition and structure of native bone tissue, as well as appropriate selection of …

Bacterial biopolymers: from pathogenesis to advanced materials

MF Moradali, BHA Rehm - Nature Reviews Microbiology, 2020 - nature.com
Bacteria are prime cell factories that can efficiently convert carbon and nitrogen sources into
a large diversity of intracellular and extracellular biopolymers, such as polysaccharides …

Inorganic polyphosphates as storage for and generator of metabolic energy in the extracellular matrix

WEG Müller, HC Schröder, X Wang - Chemical reviews, 2019 - ACS Publications
Inorganic polyphosphates (polyP) consist of linear chains of orthophosphate residues,
linked by high-energy phosphoanhydride bonds. They are evolutionarily old biopolymers …

Molecular and biochemical approach for understanding the transition of amorphous to crystalline calcium phosphate deposits in human teeth

WEG Müller, M Neufurth, H Ushijima, R Muñoz-Espí… - Dental Materials, 2022 - Elsevier
Calcium phosphate (CaP) deposition during bone mineralization starts with the aggregation
of Posner's clusters Ca 9 (PO 4) 6 into amorphous Ca-phosphate (ACP), which then …

[HTML][HTML] The physiological polyphosphate as a healing biomaterial for chronic wounds: Crucial roles of its antibacterial and unique metabolic energy supplying …

WEG Müller, H Schepler, M Neufurth, S Wang… - Journal of Materials …, 2023 - Elsevier
Insufficient metabolic energy, in the form of adenosine triphosphate (ATP), and bacterial
infections are among the main causes for the development of chronic wounds. Previously …

Progress and applications of polyphosphate in bone and cartilage regeneration

Y Wang, M Li, P Li, H Teng, D Fan… - BioMed Research …, 2019 - Wiley Online Library
Patients with bone and cartilage defects due to infection, tumors, and trauma are quite
common. Repairing bone and cartilage defects is thus a major problem for clinicians …

3D bioprinting of tissue units with mesenchymal stem cells, retaining their proliferative and differentiating potential, in polyphosphate-containing bio-ink

M Neufurth, S Wang, HC Schröder, B Al-Nawas… - …, 2021 - iopscience.iop.org
Abstract The three-dimensional (3D)-printing processes reach increasing recognition as
important fabrication techniques to meet the growing demands in tissue engineering …

[HTML][HTML] Functional importance of coacervation to convert calcium polyphosphate nanoparticles into the physiologically active state

WEG Müller, M Neufurth, I Lieberwirth, S Wang… - Materials Today Bio, 2022 - Elsevier
Inorganic polyphosphates (polyP) are of increasing medical interest due to their
unprecedented ability to exhibit both morphogenetic and ATP-delivering properties …

[HTML][HTML] The therapeutic potential of inorganic polyphosphate: A versatile physiological polymer to control coronavirus disease (COVID-19)

H Schepler, X Wang, M Neufurth, S Wang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: The pandemic caused by the novel coronavirus SARS-CoV-2 is advancing
rapidly. In particular, the number of severe courses of the disease is still dramatically high …

Mechanistically Scoping Cell‐free and Cell‐dependent Artificial Scaffolds in Rebuilding Skeletal and Dental Hard Tissues

P Yu, F Yu, J Xiang, K Zhou, L Zhou, Z Zhang… - Advanced …, 2022 - Wiley Online Library
Rebuilding mineralized tissues in skeletal and dental systems remains costly and
challenging. Despite numerous demands and heavy clinical burden over the world, sources …