Bone‑related diseases comprise a large group of common diseases, including fractures,
osteoporosis and osteoarthritis (OA), which affect a large number of individuals, particularly …

Objectives: To qualitatively and quantitatively review the use of melatonin as a
topical/systemic formulation for the management of periodontitis. Materials and methods …

Because the chronobiotic and cytoprotective molecule melatonin diminishes with age, its
involvement in postmenopausal and senescence pathology has been considered since …

Considering the central role of inflammation in the pathogenesis of periodontitis, the
combination of NSPT with different agents that can modulate the host immune-inflammatory …

Objectives The aim of the current clinical trial was to evaluate if the oral supplementation of
melatonin after nonsurgical periodontal therapy (NSPT) determined a better periodontal …

Objective This study aimed to evaluate the effect of adjunctive melatonin supplementation
on clinical outcomes after non-surgical periodontal treatment. Methods PubMed, Embase …

Objective. Ascorbic acid (AA) and controlled inflammatory stimuli are postulated to possess
the ability to independently exert positive effects on a variety of proliferative, pluripotency …

Background and objective The antioxidant potential of vitamin C is useful in reducing
oxidative stress, free radicals, and reactive oxygen species, which may assist in the …

Background The present study aims to evaluate and compare the efficacy of locally
delivered 1% melatonin gel as an adjunct to non‐surgical periodontal therapy (NSPT) in …

The present study explored the effects of ascorbic-acid (AA)/retinol and timed inflammation
on the stemness, the regenerative potential, and the transcriptomics profile of gingival …