The field of pharmacogenetics contains a wealth of potential for the enhancement of clinical
practice by providing a more effective match between patient and drug, consequently …

Background and purpose: Monoamine oxidase inhibitors (MAOI) are known to cause
serotonin toxicity (ST) when administered with selective serotonin reuptake inhibitors (SSRI) …

A narrative review of the literature was conducted to determine if the administration of
methylene blue (MB) in humans has potential risks. Studies were identified from MEDLINE …

Serotonin syndrome is thought to arise from serotonin excess. In many cases, symptoms are
mild and self-limiting. But serotonin syndrome can become life threatening, when …

Serotonin-active drugs are detected relatively frequently in Victorian deaths. During 2002–
2008, there were 1123 fatalities where one or more of the serotonin-active drugs tramadol …

Objectives Methylene blue commonly is used as a dye or an antidote, but also can be used
off label as a vasopressor. Serotonin toxicity is a potentially lethal and often misdiagnosed …

Monoamine oxidases A and B (MAO-A and B) play a critical role in the metabolism of
intracellular neurotransmitters of the central nervous system. For decades, MAO inhibitors …

Citalopram is a very potent and highly selective inhibitor of neuronal serotonin (5-
hydroxytryptamine, or 5-HT). Serotonin syndrome is a rarely observed side-effect of …

Pflanzliche Arzneimittel erfreuen sich in vielen Ländern unterschiedlicher Kulturkreise einer
zunehmenden Beliebtheit. Der Anteil der Bevölkerung mit regelmäßiger Einnahme von …

Yew intoxication is an uncommon, life-threatening emergency. Patients frequently die due to
refractory cardiac shock or pulseless ventricular tachycardia and ventricular fibrillation, both …