Due to the wide use and key importance of mathematical models in process engineering,
experiment design is becoming an essential tool for the rapid building and validation of …

Fermenter control has been an active area of research and has attracted more attention in
recent years. This is due to the new developments in other related areas which can be …

Here we address the problem of parameter estimation (inverse problem) of nonlinear
dynamic biochemical pathways. This problem is stated as a nonlinear programming (NLP) …

Developing suitable dynamic models of biochemical pathways is a key issue in Systems
Biology. Predictive models for cells or whole organisms could ultimately lead to model …

The dynamic optimization (open loop optimal control) of non-linear bioprocesses is
considered in this contribution. These processes can be described by sets of non-linear …

In this paper an overview of optimal adaptive control of (bio) chemical reactors is presented.
Following the paradigm of the Minimum Principle of Pontryagin the derivation of optimal …

The accurate solution of optimal control problems is crucial in many areas of engineering
and applied science. For systems which are described by a nonlinear set of differential …

An enhanced scatter search method for the global dynamic optimization of nonlinear
processes using the control vector parametrization (CVP) approach is presented. Sharing …

Fed-batch fermentation is an important production technology in the biochemical industry.
Using fed-batch Saccharomyces cerevisiae fermentation as a prototypical example, we …

The extension of a recently developed method for the dynamic optimization of chemical and
biochemical processes is presented. This method is based on the control vector …