Ergosterol is an essential component of fungal cell membranes that determines the fluidity,
permeability and activity of membrane-associated proteins. Ergosterol biosynthesis is a …

Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which
is caused by more than 20 types of Candida sp., with C. albicans being the most common …

▪ Abstract The synthesis and excretion of bile acids comprise the major pathway of
cholesterol catabolism in mammals. Synthesis provides a direct means of converting …

An extracellular matrix composed of a layered meshwork of β-glucans, chitin, and
mannoproteins encapsulates cells of the yeast Saccharomyces cerevisiae. This organelle …

In this review, we discuss new insights in cell wall architecture and cell wall construction in
the ascomycetous yeast Saccharomyces cerevisiae. Transcriptional profiling studies …

The trace element zinc is required for proper functioning of a large number of proteins,
including various enzymes. However, most zinc-containing proteins are transcription factors …

Cholesterol is an essential component of mammalian cell membranes and is required for
proper membrane permeability, fluidity, organelle identity, and protein function. Cells …

Membrane lipids diffuse rapidly in the plane of the membrane but their ability to flip
spontaneously across a membrane bilayer is hampered by a significant energy barrier. Thus …

Cholesterol and fatty acid synthesis in mammals are controlled by SREBPs, a family of
membrane bound transcription factors. Our studies identified homologs of SREBP, its …

The transcriptome of a wine yeast was monitored throughout an alcoholic fermentation
under conditions mimicking an enological environment. Major changes in gene expression …