Cancer remains as one of the most significant health problems, with approximately 19
million people diagnosed worldwide each year. Chemotherapy is a routinely used method to …

Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …

Immunotherapy has made remarkable strides in cancer therapy over the past decade.
However, such emerging therapy still suffers from the low response rates and immune …

Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …

Photodynamic therapy (PDT) mostly relies on the generation of singlet oxygen, via the
excitation of a photosensitizer, so that target tumor cells can be destroyed. PDT can be …

Stimuli-responsive polymers can respond to internal stimuli, such as reactive oxygen
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …

Targeting ferroptosis, which provokes lipid peroxidation in cancer cells, presents potentially
new avenues for anticancer therapy. Recent studies have begun to explore how immune …

Photoactivation therapy based on photodynamic therapy (PDT) and photothermal therapy
(PTT) has been identified as a tumour ablation modality for numerous cancer indications …

The hypoxia microenvironment of solid tumors poses a technological bottleneck for
ferroptosis and immunotherapy in clinical oncology. Nanoreactors based on special …

Fusobacterium nucleatum (Fn), a bacterium present in the human oral cavity and rarely
found in the lower gastrointestinal tract of healthy individuals, is enriched in human …