[HTML][HTML] Transfersomes: A promising nanoencapsulation technique for transdermal drug delivery

SAT Opatha, V Titapiwatanakun, R Chutoprapat - Pharmaceutics, 2020 - mdpi.com
Transdermal delivery systems have gained much interest in recent years owing to their
advantages compared to conventional oral and parenteral delivery systems. They are …

[HTML][HTML] The influence of the gut microbiota on the bioavailability of oral drugs

X Zhang, Y Han, W Huang, M Jin, Z Gao - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …

Bile acids and their derivatives as potential modifiers of drug release and pharmacokinetic profiles

N Pavlović, S Goločorbin-Kon, M Ðanić… - Frontiers in …, 2018 - frontiersin.org
Bile acids have received considerable interest in the drug delivery research due to their
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …

Absorption-enhancing effects of bile salts

E Moghimipour, A Ameri, S Handali - Molecules, 2015 - mdpi.com
Bile salts are ionic amphiphilic compounds with a steroid skeleton. Among the most
important physiological properties of bile salts are lipid transport by solubilization and …

Niosomal carriers enhance oral bioavailability of carvedilol: effects of bile salt-enriched vesicles and carrier surface charge

G Arzani, A Haeri, M Daeihamed… - International journal …, 2015 - Taylor & Francis
Carvedilol (CRV) is an antihypertensive drug with both alpha and beta receptor blocking
activity used to preclude angina and cardiac arrhythmias. To overcome the low, variable oral …

Bilosomes as a novel carrier for the cutaneous delivery for dapsone as a potential treatment of acne: preparation, characterization and in vivo skin deposition assay

MA El-Nabarawi, RN Shamma, F Farouk… - Journal of liposome …, 2020 - Taylor & Francis
In our study, the potential of bilosomes as novel vesicular carrier for the cutaneous delivery
of the sulphone compound, Dapsone, for topical treatment of acne was investigated. The …

An update on pharmaceutical strategies for oral delivery of therapeutic peptides and proteins in adults and pediatrics

N Dan, K Samanta, H Almoazen - Children, 2020 - mdpi.com
While each route of therapeutic drug delivery has its own advantages and limitations, oral
delivery is often favored because it offers convenient painless administration, sustained …

Bioaccessibility, bioavailability and bioactivities of carotenoids in microalgae: A review

X Duan, C Xie, DRA Hill, CJ Barrow… - Food Reviews …, 2024 - Taylor & Francis
In recent years, carotenoids, as photosynthetic pigments, have drawn increasing interest
due to their health benefits. This is because carotenoids have possessed enormous …

Microbiome-mediated bile acid modification: role in intestinal drug absorption and metabolism

EF Enright, BT Griffin, CGM Gahan, SA Joyce - Pharmacological Research, 2018 - Elsevier
Once regarded obscure and underappreciated, the gut microbiota (the microbial
communities colonizing the gastrointestinal tract) is gaining recognition as an influencer of …

Pitavastatin-loaded bilosomes for oral treatment of hepatocellular carcinoma: A repurposing approach

M Kharouba, A El-Kamel, R Mehanna, E Thabet… - Drug Delivery, 2022 - Taylor & Francis
Albeit its established efficacy as an anti-hyperlipidemic agent, pitavastatin (PIT) has been
shown to have other various therapeutic effects. One of these effects is the anti-cancer …