Molecular diagnostics in the evaluation of thyroid nodules: current use and prospective opportunities

J Patel, J Klopper, EE Cottrill - Frontiers in endocrinology, 2023 - frontiersin.org
Thyroid cancer is the most common endocrine malignancy with an estimated 43,800 new
cases to be diagnosed in 2022 and representing the 7th most common cancer in women …

The incidental thyroid nodule

SB Fisher, ND Perrier - CA: a cancer journal for clinicians, 2018 - Wiley Online Library
Incidental thyroid nodules that are found on an imaging study performed for reasons other
than thyroid pathology represent a common scenario encountered by health care providers …

Multiplatform molecular test performance in indeterminate thyroid nodules

MA Lupo, AE Walts, JW Sistrunk… - Diagnostic …, 2020 - Wiley Online Library
Background Approximately 25% of thyroid nodule fine‐needle aspirates (FNAs) have
cytology that is indeterminate for malignant disease. Accurate risk stratification of these …

Thyroid nodules and cancer management guidelines: comparisons and controversies

F Nabhan, MD Ringel - Endocrine-related cancer, 2017 - erc.bioscientifica.com
Thyroid cancer is an increasingly prevalent malignancy throughout the world. Management
guidelines for both thyroid nodules and thyroid cancer have been published and updated by …

Silencing of long noncoding RNA LINC00958 prevents tumor initiation of pancreatic cancer by acting as a sponge of microRNA-330-5p to down-regulate PAX8

S Chen, JZ Chen, JQ Zhang, HX Chen, FN Qiu, ML Yan… - Cancer letters, 2019 - Elsevier
Pancreatic cancer (PC) represents a relatively rare but severe malignancy worldwide.
Accumulated studies have emphasized the potential of long noncoding RNA (lncRNA) as …

Update on molecular testing for cytologically indeterminate thyroid nodules

M Nishino, M Nikiforova - Archives of pathology & …, 2018 - meridian.allenpress.com
Context.—Approximately 15% to 30% of thyroid nodules that undergo fine-needle aspiration
are classified as cytologically indeterminate, presenting management challenges for …

Thyroid nodules: Α guide to assessment, treatment and follow-up

SΑ Paschou, A Vryonidou, DG Goulis - Maturitas, 2017 - Elsevier
Thyroid nodules constitute by far the most common disorder of the endocrine system.
Epidemiological studies have indicated that approximately 5% of women and 1% of men …

A retrospective evaluation of the diagnostic performance of an interdependent pairwise MicroRNA expression analysis with a mutation panel in indeterminate thyroid …

SD Finkelstein, JW Sistrunk, C Malchoff, DV Thompson… - Thyroid, 2022 - liebertpub.com
Background: The addition of genetic analysis to the evaluation of thyroid nodule fine-needle
aspiration biopsy samples improves diagnostic accuracy of cytologically indeterminate …

The role of molecular testing for the indeterminate thyroid FNA

ED Rossi, L Pantanowitz, WC Faquin - Genes, 2019 - mdpi.com
Thyroid nodules are common in the adult population where a majority are benign and only
4.0% to 6.5% are malignant. Fine needle aspiration (FNA) is a key method used in the early …

[HTML][HTML] BRAF V600E mutation in prognostication of papillary thyroid cancer (PTC) recurrence

A Czarniecka, M Oczko-Wojciechowska… - Gland …, 2016 - ncbi.nlm.nih.gov
Papillary thyroid cancer (PTC) offers excellent prognosis, however relapse risk or persistent
disease is related to~ 30%. Currently, attention is paid to the possibility of patient group …