The role of the gut microbiota in the relationship between diet and human health

BK Perler, ES Friedman, GD Wu - Annual review of physiology, 2023 - annualreviews.org
The interplay between diet, the gut microbiome, and host health is complex. Diets
associated with health have many similarities: high fiber, unsaturated fatty acids, and …

Clinical application of intermittent fasting for weight loss: progress and future directions

KA Varady, S Cienfuegos, M Ezpeleta… - Nature Reviews …, 2022 - nature.com
Intermittent fasting diets have become very popular in the past few years, as they can
produce clinically significant weight loss. These diets can be defined, in the simplest of …

[HTML][HTML] Effects of 4-and 6-h time-restricted feeding on weight and cardiometabolic health: a randomized controlled trial in adults with obesity

S Cienfuegos, K Gabel, F Kalam, M Ezpeleta… - Cell metabolism, 2020 - cell.com
Time-restricted feeding (TRF) regimens have grown in popularity; however, very few studies
have examined their weight-loss efficacy. We conducted the first human trial (Clinicaltrials …

Cardiometabolic benefits of intermittent fasting

KA Varady, S Cienfuegos, M Ezpeleta… - Annual review of …, 2021 - annualreviews.org
This review aims to summarize the effects of intermittent fasting on markers of
cardiometabolic health in humans. All forms of fasting reviewed here—alternate-day fasting …

Monocytes re-enter the bone marrow during fasting and alter the host response to infection

H Janssen, F Kahles, D Liu, J Downey, LL Koekkoek… - Immunity, 2023 - cell.com
Diet profoundly influences physiology. Whereas over-nutrition elevates risk for disease via
its influence on immunity and metabolism, caloric restriction and fasting appear to be …

Effects of intermittent fasting on health, aging, and disease

R De Cabo, MP Mattson - New England Journal of Medicine, 2019 - Mass Medical Soc
Effects of Intermittent Fasting on Health and Aging Evidence is accumulating that eating in a
6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to …

Oxidative stress in type 2 diabetes: impacts from pathogenesis to lifestyle modifications

A Caturano, M D'Angelo, A Mormone, V Russo… - Current Issues in …, 2023 - mdpi.com
Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its
associated complications. The imbalance between reactive oxygen species (ROS) …

[HTML][HTML] Early time-restricted feeding improves insulin sensitivity, blood pressure, and oxidative stress even without weight loss in men with prediabetes

EF Sutton, R Beyl, KS Early, WT Cefalu, E Ravussin… - Cell metabolism, 2018 - cell.com
Intermittent fasting (IF) improves cardiometabolic health; however, it is unknown whether
these effects are due solely to weight loss. We conducted the first supervised controlled …

Intermittent and periodic fasting, longevity and disease

VD Longo, M Di Tano, MP Mattson, N Guidi - Nature aging, 2021 - nature.com
Intermittent and periodic fasting (IF and PF, respectively) are emerging as safe strategies to
affect longevity and healthspan by acting on cellular aging and disease risk factors, while …

Flipping the metabolic switch: understanding and applying the health benefits of fasting

SD Anton, K Moehl, WT Donahoo, K Marosi, SA Lee… - …, 2018 - Wiley Online Library
Objective Intermittent fasting (IF) is a term used to describe a variety of eating patterns in
which no or few calories are consumed for time periods that can range from 12 hours to …