Vitamin B3 (nicotinic acid, niacin) deficiency causes the systemic disease pellagra, which
leads to dermatitis, diarrhea, dementia, and possibly death depending on its severity and …

Melanosomes are specialized intracellular organelles that produce and store melanin
pigments in melanocytes, which are present in several mammalian tissues and organs …

The epidermis is located in the outermost layer of the living body and is the place where
external stimuli such as ultraviolet rays and microorganisms first come into contact …

Melanosomes are specialized membrane-bound organelles that synthesize and organize
melanin, ultimately providing color to the skin, hair, and eyes. Disorders in melanogenesis …

Melanocytes produce melanin to protect the skin from UV-B radiation. Notwithstanding, the
spectrum of their functions extends far beyond their well-known role as melanin production …

In Asia, the market for whitening cosmetics is expanding rapidly, more and more people
prefer to use natural products. Driven by natural product demand and technical advances …

Cutaneous pigmentation was recently shown to be an event regulated by clock proteins.
Cryptochrome (CRY) is a key protein composing the feedback loop of circadian clock …

Increasing evidence suggests that human epidermal melanocytes play an important role in
the skin immune system; however, a role of their pigmentation in immune and inflammatory …

Background The main pathogenesis of acne vulgaris is increase in sebum production and
abnormal keratinization of the hair infundibulum. The androgens are involved in acne …

Diazepam is a medicament of the benzodiazepine family and it typically produces a sedative
effect. Researchers have revealed that diazepam can induce melanogenesis and produce …