New horizons in human sperm selection for assisted reproduction
B Nixon, JE Schjenken, ND Burke… - Frontiers in …, 2023 - frontiersin.org
Male infertility is a commonly encountered pathology that is estimated to be a contributory
factor in approximately 50% of couples seeking recourse to assisted reproductive …
factor in approximately 50% of couples seeking recourse to assisted reproductive …
The role of sperm proteins IZUMO1 and TMEM95 in mammalian fertilization: a systematic review
M Hernández-Falcó, P Sáez-Espinosa… - International Journal of …, 2022 - mdpi.com
Gamete membrane fusion is a critical cellular event in sexual reproduction. In addition, the
generation of knockout models has provided a powerful tool for testing the functional …
generation of knockout models has provided a powerful tool for testing the functional …
The role of spermatozoa-zona pellucida interaction in selecting fertilization-competent spermatozoa in humans
ETY Leung, BKM Lee, CL Lee, X Tian… - Frontiers in …, 2023 - frontiersin.org
Human fertilization begins when a capacitated spermatozoon binds to the zona pellucida
(ZP) surrounding a mature oocyte. Defective spermatozoa-ZP interaction contributes to male …
(ZP) surrounding a mature oocyte. Defective spermatozoa-ZP interaction contributes to male …
Proteomic analysis of sperm from fertile stallions and subfertile stallions due to impaired acrosomal exocytosis
C Hernández-Avilés, L Ramírez-Agámez… - Scientific reports, 2024 - nature.com
Thoroughbred stallions that carry a double-homozygous genotype A/AA/A for SNPs
rs397316122 and rs69101140 in exon 5 of the FKBP6 gene (chr13; EquCab3. 0) are …
rs397316122 and rs69101140 in exon 5 of the FKBP6 gene (chr13; EquCab3. 0) are …
The strong anti-hyaluronidase effect of ellagic acid markedly decreases polyspermy during in vitro fertilization, resulting in sustainment of the developmental potency …
K Kawasaki, M Hirai, Y Ishiki, A Nagahama, T Konno… - Theriogenology, 2024 - Elsevier
The present study investigated the effects of ellagic acid, a type of polyphenol that does not
have a glycan and is composed of four hydroxyl groups and two lactone functional groups …
have a glycan and is composed of four hydroxyl groups and two lactone functional groups …
Bioinformatic approach to unveil key differentially expressed proteins in human sperm after slow and rapid cryopreservation
Currently, two conventional freezing techniques are used in sperm cryopreservation: slow
freezing (SF) and rapid freezing (RF). Despite the protocolar improvements …
freezing (SF) and rapid freezing (RF). Despite the protocolar improvements …
Cordycepin improves hyperactivation and acrosome reaction through adenosine receptors during human sperm capacitation in vitro
L Shan, L Gao, Y Chai, K Li, J Yu, F Liang, J Qin… - Reproductive Biology …, 2024 - Springer
Background Sperm capacitation is a prerequisite for natural or in vitro fertilization. After
capacitation, sperm become hyperactivated and undergo an acrosome reaction, which …
capacitation, sperm become hyperactivated and undergo an acrosome reaction, which …
Establishment of a repertoire of fertility associated sperm proteins and their differential abundance in buffalo bulls (Bubalus bubalis) with contrasting fertility
Sperm harbours a wide range of proteins regulating their functions and fertility. In the
present study, we made an effort to characterize and quantify the proteome of buffalo bull …
present study, we made an effort to characterize and quantify the proteome of buffalo bull …
The stallion sperm acrosome: Considerations from a research and clinical perspective
C Hernández-Avilés, L Ramírez-Agámez, DD Varner… - Theriogenology, 2023 - Elsevier
During the fertilization process, the interaction between the sperm and the oocyte is
mediated by a process known as acrosomal exocytosis (AE). Although the role of the sperm …
mediated by a process known as acrosomal exocytosis (AE). Although the role of the sperm …
Paternal factors in recurrent pregnancy loss: an insight through analysis of non-synonymous single-nucleotide polymorphism in human testis-specific chaperone …
Heat shock protein A2 (HSPA2) is a testis-specific molecular chaperone of the 70 kDa heat
shock protein (HSP70) family and reported to play a key role in spermatogenesis as well as …
shock protein (HSP70) family and reported to play a key role in spermatogenesis as well as …