[HTML][HTML] The microRNA-200 family: small molecules with novel roles in cancer development, progression and therapy

B Humphries, C Yang - Oncotarget, 2015 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are a large family of small non-coding RNAs that negatively regulate
protein-coding gene expression post-transcriptionally via base pairing between the 5 …

[HTML][HTML] MicroRNAs in the regulation of cellular redox status and its implications in myocardial ischemia-reperfusion injury

T Carbonell, AV Gomes - Redox biology, 2020 - Elsevier
MicroRNAs (miRNAs) are small RNAs that do not encode for proteins and play key roles in
the regulation of gene expression. miRNAs are involved in a comprehensive range of …

pH‐responsive PEG‐shedding and Targeting peptide‐modified nanoparticles for dual‐delivery of Irinotecan and microRNA to enhance tumor‐specific therapy

V Juang, CH Chang, CS Wang, HE Wang, YL Lo - Small, 2019 - Wiley Online Library
Irinotecan is one of the main chemotherapeutic agents for colorectal cancer (CRC).
MicroRNA‐200 (miR‐200) has been reported to inhibit metastasis in cancer cells. Herein …

Therapeutic advancements in targeting BCL-2 family proteins by epigenetic regulators, natural, and synthetic agents in cancer

A Sarkar, A Paul, T Banerjee, A Maji, S Saha… - European Journal of …, 2023 - Elsevier
Cancer is amongst the deadliest and most disruptive disorders, having a much higher death
rate than other diseases worldwide. Human cancer rates continue to rise, thereby posing the …

MicroRNA regulation of human breast cancer stem cells

Y Shimono, J Mukohyama, S Nakamura… - Journal of clinical …, 2015 - mdpi.com
MicroRNAs (miRNAs) are involved in virtually all biological processes, including stem cell
maintenance, differentiation, and development. The dysregulation of miRNAs is associated …

[HTML][HTML] Integrated molecular signaling involving mitochondrial dysfunction and alteration of cell metabolism induced by tyrosine kinase inhibitors in cancer

MA Rodríguez-Hernández, P de la Cruz-Ojeda… - Redox Biology, 2020 - Elsevier
Cancer cells have unlimited replicative potential, insensitivity to growth-inhibitory signals,
evasion of apoptosis, cellular stress, and sustained angiogenesis, invasiveness and …

Epstein–Barr virus miR-BART20-5p regulates cell proliferation and apoptosis by targeting BAD

H Kim, H Choi, SK Lee - Cancer letters, 2015 - Elsevier
Abstract Although Epstein–Barr virus (EBV) Bam HI A rightward transcript (BART)
microRNAs (miRNAs) are ubiquitously expressed in EBV-associated tumors, the role of most …

Mini but mighty: Micro RNA s in the pathobiology of periodontal disease

M Kebschull, PN Papapanou - Periodontology 2000, 2015 - Wiley Online Library
Micro RNA s (mi RNA s) are a family of small, noncoding RNA molecules that negatively
regulate protein expression either by inhibiting initiation of the translation of mRNA or by …

Urinary sediment miRNA levels in adult nephrotic syndrome

G Wang, BCH Kwan, FMM Lai, KM Chow, PKT Li… - Clinica chimica acta, 2013 - Elsevier
BACKGROUND: MicroRNAs are a group of non-coding RNA molecules that play important
roles in the pathogenesis of various kidney diseases. We investigate the urinary sediment …

Pro-death signaling of cytoprotective heat shock factor 1: upregulation of NOXA leading to apoptosis in heat-sensitive cells

P Janus, A Toma-Jonik, N Vydra, K Mrowiec… - Cell Death & …, 2020 - nature.com
Heat shock can induce either cytoprotective mechanisms or cell death. We found that in
certain human and mouse cells, including spermatocytes, activated heat shock factor 1 …