Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis

W Jia, G Xie, W Jia - Nature reviews Gastroenterology & hepatology, 2018 - nature.com
Emerging evidence points to a strong association between the gut microbiota and the risk,
development and progression of gastrointestinal cancers such as colorectal cancer (CRC) …

[HTML][HTML] Gut microbiota as a potential target of metabolic syndrome: the role of probiotics and prebiotics

M He, B Shi - Cell & bioscience, 2017 - Springer
Metabolic syndrome (MS) comprises central obesity, increased plasma glucose levels,
hyperlipidemia and hypertension, and its incidence is increasing due to changes in lifestyle …

Inflammatory bowel disease: clinical aspects and treatments

M Fakhoury, R Negrulj, A Mooranian… - Journal of inflammation …, 2014 - Taylor & Francis
Inflammatory bowel disease (IBD) is defined as a chronic intestinal inflammation that results
from host-microbial interactions in a genetically susceptible individual. IBDs are a group of …

[HTML][HTML] Probiotics and prebiotics: present status and future perspectives on metabolic disorders

JY Yoo, SS Kim - Nutrients, 2016 - mdpi.com
Metabolic disorders, including type 2 diabetes (T2DM) and cardiovascular disease (CVD),
present an increasing public health concern and can significantly undermine an individual's …

[HTML][HTML] Cholesterol-Lowering Effects of Probiotics and Prebiotics: A Review of in Vivo and in Vitro Findings

LG Ooi, MT Liong - International journal of molecular sciences, 2010 - mdpi.com
Probiotics are live microorganisms that promote health benefits upon consumption, while
prebiotics are nondigestible food ingredients that selectively stimulate the growth of …

Cholesterol‐lowering probiotics as potential biotherapeutics for metabolic diseases

M Kumar, R Nagpal, R Kumar… - Journal of Diabetes …, 2012 - Wiley Online Library
Cardiovascular diseases are one of the major causes of deaths in adults in the western
world. Elevated levels of certain blood lipids have been reported to be the principal cause of …

Bile salt hydrolase activity in probiotics

M Begley, C Hill, CGM Gahan - Applied and environmental …, 2006 - Am Soc Microbiol
Probiotics are defined as “living microorganisms, which upon ingestion in certain numbers
exert health benefits on the host beyond inherent basic nutrition”(43). Various studies have …

Cholesterol-lowering efficacy of a microencapsulated bile salt hydrolase-active Lactobacillus reuteri NCIMB 30242 yoghurt formulation in hypercholesterolaemic …

ML Jones, CJ Martoni, M Parent… - British Journal of Nutrition, 2012 - cambridge.org
Several studies have reported limited or no reduction in serum cholesterol in response to
probiotic formulations. Recently, probiotics have shown promise in treating metabolic …

Therapeutic modulation of microbiota-host metabolic interactions

E Holmes, J Kinross, GR Gibson, R Burcelin… - Science translational …, 2012 - science.org
The complex metabolic relationships between the host and its microbiota change throughout
life and vary extensively between individuals, affecting disease risk factors and therapeutic …

Feeding our immune system: impact on metabolism

I Wolowczuk, C Verwaerde, O Viltart… - Journal of …, 2008 - Wiley Online Library
Endogenous intestinal microflora and environmental factors, such as diet, play a central role
in immune homeostasis and reactivity. In addition, microflora and diet both influence body …