Intense genome sequencing of Pseudomonas aeruginosa isolates from cystic fibrosis (CF)
airways has shown inefficient eradication of the infecting bacteria, as well as previously …

Antimicrobial resistance is an old and silent pandemic. Resistant organisms emerge in
parallel with new antibiotics, leading to a major global public health crisis over time …

In recent years, the worldwide spread of the so-called high-risk clones of multidrug-resistant
or extensively drug-resistant (MDR/XDR) Pseudomonas aeruginosa has become a public …

Bacteriophage particles are the most abundant biological entities on our planet, infecting
specific bacterial hosts in every known environment and being major drivers of bacterial …

Chronic lower airway infection with Pseudomonas aeruginosa is a major contributor to
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …

Pseudomonas aeruginosa is a major opportunistic pathogen, causing a wide range of acute
and chronic infections. β-lactam antibiotics including penicillins, carbapenems …

At present, anti-virulence drugs are being considered as potential therapeutic alternatives
and/or adjuvants to currently failing antibiotics. These drugs do not kill bacteria but inhibit …

Antibiotic resistance is a problem for human health, and consequently, its study had been
traditionally focused toward its impact for the success of treating human infections in …

One of the most striking features of Pseudomonas aeruginosa is its outstanding capacity for
developing antimicrobial resistance to nearly all available antipseudomonal agents through …

Collateral sensitivity (CS) is an evolutionary trade-off traditionally linked to the mutational
acquisition of antibiotic resistance (AR). However, AR can be temporally induced, and the …