Cyclin-dependent kinases in breast cancer: expression pattern and therapeutic implications
Presently, breast cancer (BC) is one of the most common malignancies diagnosed and the
leading cause of tumor-related deaths among women worldwide. Cell cycle dysregulation is …
leading cause of tumor-related deaths among women worldwide. Cell cycle dysregulation is …
Targeting cyclin-dependent kinase 1 (CDK1) in cancer: molecular docking and dynamic simulations of potential CDK1 inhibitors
Cell cycle dysregulation is a characteristic hallmark of malignancies, which results in
uncontrolled cell proliferation and eventual tumor formation. Cyclin-dependent kinase 1 …
uncontrolled cell proliferation and eventual tumor formation. Cyclin-dependent kinase 1 …
Expression patterns and therapeutic implications of CDK4 across multiple carcinomas: a molecular docking and MD simulation study
The CDKs are known to play a critical role in cell cycle regulation process. Among the
different groups of CDKs, CDK4 overexpression/hyperactivation is found to be present in …
different groups of CDKs, CDK4 overexpression/hyperactivation is found to be present in …
Identification and analysis of dysregulated fatty acid metabolism genes in breast cancer subtypes
Breast cancer is one of the most aggressive and lethal types of transformation among
women. An anomaly of normal fatty acid metabolism is acknowledged as a critical trigger for …
women. An anomaly of normal fatty acid metabolism is acknowledged as a critical trigger for …
Proteomics: a groundbreaking development in cancer biology
Proteins are the basic unit of any living organism. Proteins are comprised of a variety of
amino acids that drive the structure, stability, and function of proteins. Proteins are the …
amino acids that drive the structure, stability, and function of proteins. Proteins are the …
[HTML][HTML] Decoding the molecular mechanism of stypoldione against breast cancer through network pharmacology and experimental validation
Breast cancer is the primary factor contributing to female mortality worldwide. The incidence
has overtaken lung cancer. It is the most difficult illness due to its heterogeneity and is made …
has overtaken lung cancer. It is the most difficult illness due to its heterogeneity and is made …
Proteomics: application of next-generation proteomics in cancer research
Understanding tumor progression and carcinogenesis requires a detailed study of proteins
that play a significant role in the regulation of pathways and processes. Proteins are the …
that play a significant role in the regulation of pathways and processes. Proteins are the …
Network pharmacology and experimental validation for deciphering the action mechanism of Fritillaria cirrhosa D. Don constituents in suppressing breast carcinoma
BA Bhat, W Rashid Mir, M Alkhanani… - Journal of …, 2023 - Taylor & Francis
Fritillaria cirrhosa D. Don is a well-known medicinal plant of Kashmir Himalaya. Traditionally,
it has been used to treat several diseases, including cancer. However, the molecular …
it has been used to treat several diseases, including cancer. However, the molecular …
Introduction to breast cancer
Breast cancer is the leading cause of mortality among women worldwide. Being a
heterogenous disease it comprises many different subtypes that differ in their pathological …
heterogenous disease it comprises many different subtypes that differ in their pathological …
[HTML][HTML] Prognostic significance and expression pattern of glucose related genes in breast cancer: A comprehensive computational biology approach
B Alshehri - Saudi Journal of Biological Sciences, 2024 - Elsevier
Breast cancer (BC) is the most common type of malignancy globally and the main reason
why women die from tumours. The Warburg effect, a characteristic of tumor, describes how …
why women die from tumours. The Warburg effect, a characteristic of tumor, describes how …