Autism spectrum disorder: neurodevelopmental risk factors, biological mechanism, and precision therapy
L Wang, B Wang, C Wu, J Wang, M Sun - International journal of …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism …
neurodevelopmental disorder. Over the past two decades, the prevalence of autism …
Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications
CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
An update on pharmacotherapy of autism spectrum disorder in children and adolescents
To date, no medication is proven to be effective in treating core symptoms of autism
spectrum disorder (ASD). Psychotropic medications are widely used to target emotional and …
spectrum disorder (ASD). Psychotropic medications are widely used to target emotional and …
[HTML][HTML] Emerging biomarkers in autism spectrum disorder: a systematic review
Autism spectrum disorder (ASD) affects approximately 2% of children in the United States
(US) yet its etiology is unclear and effective treatments are lacking. Therapeutic interventions …
(US) yet its etiology is unclear and effective treatments are lacking. Therapeutic interventions …
Intranasal oxytocin in the treatment of autism spectrum disorders: A multilevel meta-analysis
Intranasal oxytocin has been shown to promote social functioning and has recently been
applied as a treatment for autism spectrum disorders (ASD). The current meta-analysis aims …
applied as a treatment for autism spectrum disorders (ASD). The current meta-analysis aims …
Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity
Background Current neuroimaging perspectives on a variety of mental disorders emphasize
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …
Social skills deficits in autism spectrum disorder: potential biological origins and progress in developing therapeutic agents
RE Frye - CNS drugs, 2018 - Springer
Autism spectrum disorder is defined by two core symptoms: a deficit in social communication
and the presence of repetitive behaviors and/or restricted interests. Currently, there is no US …
and the presence of repetitive behaviors and/or restricted interests. Currently, there is no US …
Effect of intranasal oxytocin on the core social symptoms of autism spectrum disorder: a randomized clinical trial
Although small-scale studies have described the effects of oxytocin on social deficits in
autism spectrum disorder (ASD), no large-scale study has been conducted. In this …
autism spectrum disorder (ASD), no large-scale study has been conducted. In this …
Nose-to-brain peptide delivery–the potential of nanotechnology
E Samaridou, MJ Alonso - Bioorganic & medicinal chemistry, 2018 - Elsevier
Abstract Nose-to-brain (N-to-B) delivery offers to protein and peptide drugs the possibility to
reach the brain in a non-invasive way. This article is a comprehensive review of the state-of …
reach the brain in a non-invasive way. This article is a comprehensive review of the state-of …
Infrequent intranasal oxytocin followed by positive social interaction improves symptoms in autistic children: a pilot randomized clinical trial
Introduction: There are currently no approved drug interventions for social behavior
dysfunction in autism spectrum disorder (ASD). Previous trials investigating effects of daily …
dysfunction in autism spectrum disorder (ASD). Previous trials investigating effects of daily …