Hemoglobinopathies are the most common single-gene disorders in the world. Their
prevalence is predicted to increase in the future, and low-income hemoglobinopathy …

Evaluation of clinical genetics services (CGS), including genetic counseling and genetic
testing, has been problematic. Patient mortality and morbidity are unlikely to be directly …

Diagnosis of haemoglobinopathies, including thalassaemias, can result from either a clinical
suspicion of a disorder of globin chain synthesis or from follow-up of an abnormality …

Background Disparity exists in maternal and infant birth outcomes of Black and Minority
Ethnic (BAME) women giving birth in the United Kingdom (UK) compared to the majority …

Background Iron deficiency anaemia is a common problem in pregnancy despite national
recommendations and guidelines for treatment. The aim of this study was to appraise the …

OBJECTIVES: First to develop a consensus on what is known about men's experiences and
involvement in antenatal screening, second to understand whether screening is an …

Purpose Current practice recommendations support the widespread implementation of
reproductive genetic carrier screening (RGCS). These consensus-based recommendations …

Genetic screening and health-care guidelines recommend that programmes should facilitate
informed choice. It is therefore important that accurate measures of informed choice are …

There is currently no consensus on the key outcomes of reproductive genetic carrier
screening (RGCS). This has led to a large amount of variability in approaches to research …

Background In cluster randomised controlled trials (cRCTs), groups of individuals (rather
than individuals) are randomised to minimise the risk of contamination and/or efficiently use …