Older adults do not sleep as well as younger adults. Why? What alterations in sleep quantity
and quality occur as we age, and are there functional consequences? What are the …

Age-related changes in sleep and circadian regulation occur as early as the middle years of
life. Research also suggests that sleep and circadian rhythms are regulated differently …

The view that sleep is essential for survival is supported by the ubiquity of this behavior, the
apparent existence of sleep-like states in the earliest animals, and the fact that severe sleep …

Sleep is an evolutionarily conserved state that supports brain functions, including synaptic
plasticity, in species across the animal kingdom. Here, we examine the neuroanatomical …

As the aging population grows, the need to understand age‐related changes in health is
vital. Two prominent behavioral changes that occur with age are disrupted sleep and …

New Findings What is the topic of this review? This review examines the notion that
obstructive sleep apnoea (OSA) and intermittent hypoxia (IH) have hormetic effects on …

Angelica sinensis polysaccharide (ASP) is one of the principal active components of
Angelica sinensis (AS) that is widely used in natural medicine and has various …

Sleep pressure and sleep depth are key regulators of wake and sleep. Current methods of
measuring these parameters in Drosophila melanogaster have low temporal resolution …

Endogenous circadian oscillators regulate molecular, cellular and physiological rhythms,
synchronizing tissues and organ function to coordinate activity and metabolism with …

Why do some individuals need more sleep than others? Forward mutagenesis screens in
flies using engineered mutations have established a clear genetic component to sleep …