[HTML][HTML] Emerging phagocytosis checkpoints in cancer immunotherapy

Y Liu, Y Wang, Y Yang, L Weng, Q Wu… - Signal transduction and …, 2023 - nature.com
Cancer immunotherapy, mainly including immune checkpoints-targeted therapy and the
adoptive transfer of engineered immune cells, has revolutionized the oncology landscape as …

Defining the role of natural killer cells in COVID-19

MJ Lee, CA Blish - Nature immunology, 2023 - nature.com
Natural killer (NK) cells are critical effectors of antiviral immunity. Researchers have
therefore sought to characterize the NK cell response to coronavirus disease 2019 (COVID …

[HTML][HTML] Immunity to enteric viruses

A Lockhart, D Mucida, R Parsa - Immunity, 2022 - cell.com
Pathogenic enteric viruses are a major cause of morbidity and mortality, particularly among
children in developing countries. The host response to enteric viruses occurs primarily within …

[HTML][HTML] Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection

D Munnur, Q Teo, D Eggermont, HHY Lee, F Thery… - Nature …, 2021 - nature.com
Ubiquitin-like protein ISG15 (interferon-stimulated gene 15)(ISG15) is a ubiquitin-like
modifier induced during infections and involved in host defense mechanisms. Not …

[HTML][HTML] Clinico-histopathologic and single-nuclei RNA-sequencing insights into cardiac injury and microthrombi in critical COVID-19

MI Brener, ML Hulke, N Fukuma, S Golob, RS Zilinyi… - JCI insight, 2022 - ncbi.nlm.nih.gov
Acute cardiac injury is prevalent in critical COVID-19 and associated with increased
mortality. Its etiology remains debated, as initially presumed causes—myocarditis and …

Professional killers: The role of extracellular vesicles in the reciprocal interactions between natural killer, CD8+ cytotoxic T‐cells and tumour cells

F Del Vecchio, V Martinez‐Rodriguez… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) mediate the cross‐talk between cancer cells and the cells of the
surrounding Tumour Microenvironment (TME). Professional killer cells include Natural Killer …

SARS-CoV-2 infection alters mitochondrial and cytoskeletal function in human respiratory epithelial cells mediated by expression of spike protein

BH Yeung-Luk, GA Narayanan, B Ghosh, A Wally… - Mbio, 2023 - Am Soc Microbiol
ABSTRACT Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2, SCV2), which has resulted in higher morbidity and …

Protective HLA alleles against severe COVID-19: HLA-A* 68 as an ancestral protection allele in Tapachula-Chiapas, Mexico

S Hernández-Doño, RA Sánchez-González… - Clinical …, 2022 - Elsevier
HLA is a polymorphic antigen presenter which has provided valuable information on the
susceptibility of populations to viruses. Therefore, the study of HLA can reveal specific …

[HTML][HTML] Diverse roles of lung macrophages in the immune response to influenza A virus

H Li, A Wang, Y Zhang, F Wei - Frontiers in Microbiology, 2023 - frontiersin.org
Influenza viruses are one of the major causes of human respiratory infections and the newly
emerging and re-emerging strains of influenza virus are the cause of seasonal epidemics …

[HTML][HTML] Molecular mechanisms of anti-neoplastic and immune stimulatory properties of oncolytic Newcastle disease virus

V Schirrmacher - Biomedicines, 2022 - mdpi.com
Oncolytic viruses represent interesting anti-cancer agents with high tumor selectivity and
immune stimulatory potential. The present review provides an update of the molecular …