Extraintestinal pathogenic E. coli (ExPEC) are facultative pathogens that are part of the
normal human intestinal flora. The ExPEC group includes uropathogenic E. coli (UPEC) …

New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …

Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …

Antimicrobials are important tools for the therapy of infectious bacterial diseases in
companion animals. Loss of efficacy of antimicrobial substances can seriously compromise …

Klebsiella pneumoniae carbapenemases (KPCs) were originally identified in the USA in
1996. Since then, these versatile β-lactamases have spread internationally among Gram …

Hosts and bacteria have coevolved over millions of years, during which pathogenic bacteria
have modified their virulence mechanisms to adapt to host defense systems. Although the …

CTX-M β-lactamases are considered a paradigm in the evolution of a resistance
mechanism. Incorporation of different chromosomal bla CTX-M related genes from different …

Escherichia coli sequence type 131 (ST131) is a globally disseminated, multidrug resistant
(MDR) clone responsible for a high proportion of urinary tract and bloodstream infections …

Escherichia coli remains one of the most frequent causes of several common bacterial
infections in humans and animals. E. coli is the prominent cause of enteritis, urinary tract …

Background Antibiotic-resistant bacteria (ARB) present a global public health problem. With
numbers of community-acquired resistant infections increasing, understanding the …