Estimation of drug–excipient interactions is a crucial step in preformulation studies of drug
development to achieve consistent stability, bioavailability and manufacturability of solid …

Background The drug-excipient compatibility studies were carried out with the possible
excipients viz. Tween 80, Carbopol 940, chitosan, sodium alginate, and polycaprolactone …

Aceclofenac-loaded poly (vinyl-pyrrolidone)-based nanofiber formulations were prepared by
electrospinning to obtain drug-loaded orally disintegrating webs to enhance the solubility …

In this study, we investigated the formation of a co-amorphous system of tranilast (TRL) and
diphenhydramine hydrochloride (DPH), which are drugs used for treating allergies and …

Several tests should be performed to rule out any potential physical or chemical interactions
between the active pharmaceutical ingredient and the various excipients that might be …

The objectives of the present study were to develop a controlled-release bilayered tablet of
aceclofenac (AFN) 200 mg with dual release and to gain a mechanistic understanding of the …

This work proposes the design of novel oral disintegrating tablets (ODTs) of loperamide HCl
with special emphasis on disintegration and dissolution studies. The main goal was …

Developing the drugs as amphiphilic lipid complexes is a potential approach for improving
therapeutic efficacy of the drugs by increasing solubility, reducing drug crystallinity …

Objectives To design oral controlled release (CR) hydrogel matrix tablets of etamsylate
using various hydrophilic polymers. Additionally, to predict plasma concentration-time …

Application of thermogravimetry (TG) alone to study compatibility/incompatibility of active
pharmaceutical ingredients (APIs) with excipients yields to misleading results due to …