MicroRNA regulatory networks in human adipose tissue and obesity

P Arner, A Kulyté - Nature Reviews Endocrinology, 2015 - nature.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and,
therefore, biological processes in different tissues. A major function of miRNAs in adipose …

Adipose organ development and remodeling

S Cinti - Comprehensive Physiology, 2018 - iris.univpm.it
During the last decades, research on adipose tissues has spread in parallel with the
extension of obesity. Several observations converged on the idea that adipose tissues are …

[HTML][HTML] Epidemiologic, genetic, pathogenic, metabolic, epigenetic aspects involved in NASH-HCC: current therapeutic strategies

J Gutiérrez-Cuevas, S Lucano-Landeros… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is an aggressive human cancer and is
caused as consequences of chronic liver diseases. Although HCC is more common in …

[HTML][HTML] miRNA signature in NAFLD: a turning point for a non-invasive diagnosis

P Dongiovanni, M Meroni, M Longo, S Fargion… - International journal of …, 2018 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) defines a wide pathological spectrum ranging from
simple steatosis to nonalcoholic steatohepatitis (NASH) which may predispose to liver …

[HTML][HTML] Emerging role of microRNAs in lipid metabolism

Z Yang, T Cappello, L Wang - Acta Pharmaceutica Sinica B, 2015 - Elsevier
Abstract microRNAs (miRNAs or miRs) are small non-coding RNAs that are involved in post-
transcriptional regulation of their target genes in a sequence-specific manner. Emerging …

MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis

M Hulsmans, DD Keyzer, P Holvoet - The FASEB Journal, 2011 - Wiley Online Library
ABSTRACT A primary event in atherogenesis is the infiltration of activated inflammatory cells
into the arterial wall. There they secrete reactive oxygen species and oxidize lipoproteins …

Microvesicles/exosomes as potential novel biomarkers of metabolic diseases

G Müller - Diabetes, metabolic syndrome and obesity: targets and …, 2012 - Taylor & Francis
Biomarkers are of tremendous importance for the prediction, diagnosis, and observation of
the therapeutic success of common complex multifactorial metabolic diseases, such as type …

Epigenetics in non-alcoholic fatty liver disease

J Lee, Y Kim, S Friso, SW Choi - Molecular aspects of medicine, 2017 - Elsevier
Non-alcoholic fatty liver disease (NAFLD), a common hepatic disorder ranging from simple
steatosis through steatohepatitis to fibrosis and cirrhosis, is an emerging health concern …

[HTML][HTML] Circulating microRNA-150 serum levels predict survival in patients with critical illness and sepsis

C Roderburg, M Luedde, D Vargas Cardenas, M Vucur… - PloS one, 2013 - journals.plos.org
Background and Aims Down-regulation of miR-150 was recently linked to inflammation and
bacterial infection. Furthermore, reduced serum levels of miR-150 were reported from a …

micro RNA‐122 regulates hypoxia‐inducible factor‐1 and vimentin in hepatocytes and correlates with fibrosis in diet‐induced steatohepatitis

T Csak, S Bala, D Lippai, A Satishchandran… - Liver …, 2015 - Wiley Online Library
Background & Aims miR‐122 is the most abundant mi RNA in the liver particularly in
hepatocytes where it targets cholesterol metabolism. Steatosis, a key component of non …