Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

I Jurado-Martín, M Sainz-Mejías… - International journal of …, 2021 - mdpi.com
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Maintaining integrity under stress: envelope stress response regulation of pathogenesis in gram-negative bacteria

CL Hews, T Cho, G Rowley, TL Raivio - Frontiers in cellular and …, 2019 - frontiersin.org
The Gram-negative bacterial envelope is an essential interface between the intracellular
and harsh extracellular environment. Envelope stress responses (ESRs) are crucial to the …

The Extracellular Matrix Component Psl Provides Fast-Acting Antibiotic Defense in Pseudomonas aeruginosa Biofilms

N Billings, M Ramirez Millan, M Caldara… - PLoS …, 2013 - journals.plos.org
Bacteria within biofilms secrete and surround themselves with an extracellular matrix, which
serves as a first line of defense against antibiotic attack. Polysaccharides constitute major …

Oxidative Stress Response in Pseudomonas aeruginosa

WS da Cruz Nizer, V Inkovskiy, Z Versey, N Strempel… - Pathogens, 2021 - mdpi.com
Pseudomonas aeruginosa is a Gram-negative environmental and human opportunistic
pathogen highly adapted to many different environmental conditions. It can cause a wide …

New technologies for studying biofilms

MJ Franklin, C Chang, T Akiyama… - Microbial …, 2015 - Wiley Online Library
The results of recent biofilm characterizations have helped reveal the complexities of these
surface‐associated communities of microorganisms. The activities of the cells and the …

Efficacy and safety of liposomal clarithromycin and its effect on Pseudomonas aeruginosa virulence factors

M Alhajlan, M Alhariri, A Omri - Antimicrobial agents and …, 2013 - Am Soc Microbiol
We investigated the efficacy and safety of liposomal clarithromycin formulations with different
surface charges against clinical isolates of Pseudomonas aeruginosa from the lungs of …

Amber‐codon suppression for spatial localization and in vivo photoaffinity capture of the interactome of the Pseudomonas aeruginosa rare lipoprotein A lytic …

LF Avila‐Cobian, H Hoshino, ME Horsman… - Protein …, 2023 - Wiley Online Library
The 11 lytic transglycosylases of Pseudomonas aeruginosa have overlapping activities in
the turnover of the cell‐wall peptidoglycan. Rare lipoprotein A (RlpA) is distinct among the …

Comparison of 4-plex to 8-plex iTRAQ quantitative measurements of proteins in human plasma samples

G Pottiez, J Wiederin, HS Fox… - Journal of proteome …, 2012 - ACS Publications
Methods for isobaric tagging of peptides, iTRAQ or TMT, are commonly used platforms in
mass spectrometry based quantitative proteomics. These two methods are very often used to …

A Pseudomonas fluorescens type 6 secretion system is related to mucoidy, motility and bacterial competition

V Decoin, M Gallique, C Barbey, F Le Mauff, CD Poc… - BMC microbiology, 2015 - Springer
Background Pseudomonas fluorescens strain MFE01 secretes in abundance two Hcp
proteins (haemolysin co-regulated proteins) Hcp1 and Hcp2, characteristic of a functional …

Efficacy of liposomal bismuth-ethanedithiol-loaded tobramycin after intratracheal administration in rats with pulmonary Pseudomonas aeruginosa infection

M Alhariri, A Omri - Antimicrobial agents and chemotherapy, 2013 - Am Soc Microbiol
We sought to investigate alterations in quorum-sensing signal molecule N-acyl homoserine
lactone secretion and in the release of Pseudomonas aeruginosa virulence factors, as well …