Most adult organs contain regenerative stem cells, often organized in specific niches. Stem
cell function is critical for tissue homeostasis and repair upon injury, and it is dependent on …

During the last decades, remarkable progress has been made in further understanding the
complex molecular regulatory networks that maintain hematopoietic stem cell (HSC) …

Ageing impairs the ability of neural stem cells (NSCs) to transition from quiescence to
proliferation in the adult mammalian brain. Functional decline of NSCs results in the …

Comprehensive proteomics studies of human hematopoietic stem and progenitor cells
(HSPC) have revealed that aging of the HSPC compartment is characterized by elevated …

Aging impairs the ability of neural stem cells to transition from quiescence to activation
(proliferation) in the adult mammalian brain. Neural stem cell (NSC) functional decline …

It has been reported that glycogen in Escherichia coli has two structural states, that is,
fragility and stability, which alters dynamically. However, molecular mechanisms behind the …

Dysfunctional adipocyte precursors have emerged as key determinants for obesity‐and
aging‐related inflammation, but the mechanistic basis remains poorly understood. Here, we …

Introduction Fertility rates in developing countries have declined over the past decades, and
the trend of delayed fatherhood is rising as societies develop. The reasons behind the …

The Janus kinase 2 (JAK2)-driven myeloproliferative neoplasms (MPNs) are associated with
clonal myelopoiesis, elevated risk of death due to thrombotic complications, and …

Human lifespan is now longer than ever and, as a result, modern society is getting older.
Despite that, the detailed mechanisms behind the ageing process and its impact on various …