[HTML][HTML] Cancer and apoptosis: The apoptotic activity of plant and marine natural products and their potential as targeted cancer therapeutics

GS Chaudhry, A Md Akim, YY Sung… - Frontiers in …, 2022 - frontiersin.org
Cancer is a multifactorial, multi-stage disease, including complex cascades of signaling
pathways—the cell growth governed by dysregulated and abrupt cell division. Due to the …

Sweet marjoram: a review of ethnopharmacology, phytochemistry, and biological activities

F Bina, R Rahimi - Journal of evidence-based …, 2017 - journals.sagepub.com
Origanum majorana L. commonly known as sweet marjoram has been used for variety of
diseases in traditional and folklore medicines, including gastrointestinal, ocular …

Isolation and identification of chemical constituents from Origanum majorana and investigation of antiproliferative and antioxidant activities

R Erenler, O Sen, H Aksit, I Demirtas… - Journal of the …, 2016 - Wiley Online Library
BACKGROUND Origanum majorana L., belonging to the Lamiaceae family, has great
potential and has been used as a folk medicine against asthma, indigestion, headache and …

[HTML][HTML] Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide …

F Barbieri, AG Bosio, A Pattarozzi, M Tonelli… - Journal of Experimental …, 2022 - Springer
Background Chloride intracellular channel-1 (CLIC1) activity controls glioblastoma
proliferation. Metformin exerts antitumor effects in glioblastoma stem cells (GSCs) inhibiting …

[HTML][HTML] Extraction, Chemical Composition, and Anticancer Potential of Origanum onites L. Essential Oil

K Spyridopoulou, E Fitsiou, E Bouloukosta… - Molecules, 2019 - mdpi.com
Origanum species are plants rich in volatile oils that are mainly used for culinary purposes.
In recent years, there has been a growing interest in the biological activities of their essential …

[HTML][HTML] Rhus coriaria suppresses angiogenesis, metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and nitric oxide pathways

H El Hasasna, A Saleh, HA Samri, K Athamneh… - Scientific reports, 2016 - nature.com
Recently, we reported that Rhus coriaria exhibits anticancer activities by promoting cell cycle
arrest and autophagic cell death of the metastatic triple negative MDA-MB-231 breast cancer …

[HTML][HTML] Origanum majorana Essential Oil Triggers p38 MAPK-Mediated Protective Autophagy, Apoptosis, and Caspase-Dependent Cleavage of P70S6K in …

K Athamneh, A Alneyadi, H Alsamri, A Alrashedi… - Biomolecules, 2020 - mdpi.com
Colorectal cancer (CRC) is the third most common type of cancer in terms of incidence and
mortality worldwide. Here we have investigated the anti-colon cancer potential of Origanum …

[HTML][HTML] In vitro cytotoxicity and anticancer effects of citral nanostructured lipid carrier on MDA MBA-231 human breast cancer cells

N Nordin, SK Yeap, HS Rahman, NR Zamberi, N Abu… - Scientific reports, 2019 - nature.com
Very recently, we postulated that the incorporation of citral into nanostructured lipid carrier
(NLC-Citral) improves solubility and delivery of the citral without toxic effects in vivo. Thus …

[HTML][HTML] Gasotransmitters in the tumor microenvironment: Impacts on cancer chemotherapy

A Salihi, MA Al‑Naqshabandi… - Molecular …, 2022 - spandidos-publications.com
Nitric oxide, carbon monoxide and hydrogen sulfide are three endogenous gasotransmitters
that serve a role in regulating normal and pathological cellular activities. They can stimulate …

[HTML][HTML] Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells

A AlKahlout, M Fardoun, J Mesmar, R Abdallah… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is the leading cause of cancer-related deaths among women. Among breast
cancer types, triple negative breast cancer (TNBC) is the most aggressive, and is resistant to …