Strategic approaches to improvise peptide drugs as next generation therapeutics
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …
Recent advances: peptides and self-assembled peptide-nanosystems for antimicrobial therapy and diagnosis
P Zou, WT Chen, T Sun, Y Gao, LL Li, H Wang - Biomaterials Science, 2020 - pubs.rsc.org
Bacterial infections, especially the refractory treatment of drug-resistant bacteria, are one of
the greatest threats to human health. During the past decades, biomedical nanomaterials …
the greatest threats to human health. During the past decades, biomedical nanomaterials …
Antimicrobial peptides as anti-infective agents in pre-post-antibiotic era?
Resistance to antibiotics is one of the main current threats to human health and every year
multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a …
multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a …
Role and modulation of the secondary structure of antimicrobial peptides to improve selectivity
Y Liang, X Zhang, Y Yuan, Y Bao, M Xiong - Biomaterials Science, 2020 - pubs.rsc.org
Since the development of bacterial resistance, the decreasing effectiveness of antibiotics is
becoming one of the most critical problems worldwide. Novel antibacterial agents are …
becoming one of the most critical problems worldwide. Novel antibacterial agents are …
Anisaxins, helical antimicrobial peptides from marine parasites, kill resistant bacteria by lipid extraction and membrane disruption
An infecting and propagating parasite relies on its innate defense system to evade the host's
immune response and to survive challenges from commensal bacteria. More so for the …
immune response and to survive challenges from commensal bacteria. More so for the …
Cationic amphiphilic peptides: Synthetic antimicrobial agents inspired by nature
R Kundu - ChemMedChem, 2020 - Wiley Online Library
Antimicrobial peptides are ubiquitous in multicellular organisms and have served as
defense mechanisms for their successful evolution and throughout their life cycle. These …
defense mechanisms for their successful evolution and throughout their life cycle. These …
Potent and broad-spectrum antimicrobial activity of analogs from the scorpion peptide stigmurin
B Amorim-Carmo, A Daniele-Silva… - International journal of …, 2019 - mdpi.com
Scorpion venom constitutes a rich source of biologically active compounds with high
potential for therapeutic and biotechnological applications that can be used as prototypes for …
potential for therapeutic and biotechnological applications that can be used as prototypes for …
The potential of modified and multimeric antimicrobial peptide materials as superbug killers
Antimicrobial peptides (AMPs) are found in nearly all living organisms, show broad spectrum
antibacterial activity, and can modulate the immune system. Furthermore, they have a very …
antibacterial activity, and can modulate the immune system. Furthermore, they have a very …
Glycine‐replaced epinecidin‐1 variant bestows better stability and stronger antimicrobial activity against a range of nosocomial pathogenic bacteria
S Jeyarajan, AS Peter, S Ranjith… - Biotechnology and …, 2024 - Wiley Online Library
Abstract Epinecidin‐1 (epi‐1), an antimicrobial peptide first identified in marine grouper fish,
has multifunctional bioactivities. The present study aims to improve its therapeutic potential …
has multifunctional bioactivities. The present study aims to improve its therapeutic potential …
Discovery of novel quaternary ammonium compounds based on quinuclidine-3-ol as new potential antimicrobial candidates
Quaternary ammonium compounds (QACs) are amphiphilic molecules displaying a broad-
spectrum of antibacterial activity. QACs are commonly used antiseptics in industrial, home …
spectrum of antibacterial activity. QACs are commonly used antiseptics in industrial, home …