Telomerase reverse transcriptase (TERT) is a catalytic subunit of telomerase. Telomerase
complex plays a key role in cancer formation by telomere dependent or independent …

Human nuclear receptors (NRs) are a family of forty-eight transcription factors that modulate
gene expression both spatially and temporally. Numerous biochemical, physiological, and …

Transcription factor AP-2α (TFAP2A) was previously regarded as a critical regulator during
embryonic development, and its mediation in carcinogenesis has received intensive …

Angelica species have been traditionally used for their medicinal properties. Recent studies
have suggested their potential use as anticancer agents, making them an area of interest for …

Background Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer,
representing 40% of all cases of this tumor. Despite immense improvements in …

Hepatocellular cell carcinoma (HCC) is one of the most commonly diagnosed cancers
worldwide and in Taiwan. Chemoprevention of cancer with dietary bioactive compounds …

Oral cancer is a malignancy with unfavorable prognosis due to its high rates of recurrence
and lymph node metastasis. Narciclasine is extracted from Narcissus species …

Background Parkinson's disease (PD) is the second most common degenerative disorder of
the central nervous system that impairs motor skills and cognitive function. To date, the …

Down syndrome (DS) patients with early-onset dementia share similar neurodegenerative
features with Alzheimer's disease (AD). To recapitulate the AD cell model, DS induced …

Radix Angelica sinensis is a Chinese medicinal herb that has been used extensively in the
East for the treatment of cardiovascular diseases (CVDs). Angiogenesis plays an important …