The evolution of insulin and how it informs therapy and treatment choices

IB Hirsch, R Juneja, JM Beals, CJ Antalis… - Endocrine …, 2020 - academic.oup.com
Insulin has been available for the treatment of diabetes for almost a century, and the variety
of insulin choices today represents many years of discovery and innovation. Insulin has …

A review of the pharmacological properties of insulin degludec and their clinical relevance

H Haahr, T Heise - Clinical pharmacokinetics, 2014 - Springer
Insulin degludec (IDeg) is a new-generation basal insulin with an ultra-long duration of
action. To date, a large number of studies have been conducted to investigate the …

Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes …

AJ Garber, Y Handelsman, G Grunberger, D Einhorn… - Endocrine Practice, 2020 - Elsevier
ABSTRACT Abbreviations: A1C= hemoglobin A1C; AACE= American Association of Clinical
Endocrinologists; ABCD= adiposity-based chronic disease; ACCORD= Action to Control …

Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes …

AJ Garber, MJ Abrahamson, JI Barzilay, L Blonde… - Endocrine Practice, 2019 - Elsevier
ABSTRACT Abbreviations: A1C= hemoglobin A1C; AACE= American Association of Clinical
Endocrinologists; ACCORD= Action to Control Cardiovascular Risk in Diabetes; ACCORD …

Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes …

AJ Garber, MJ Abrahamson, JI Barzilay, L Blonde… - Endocrine Practice, 2017 - Elsevier
ABSTRACT Abbreviations: A1C= hemoglobin A1C AACE= American Association of Clinical
Endocrinologists ACCORD= Action to Control Cardiovascular Risk in Diabetes ACCORD …

Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes …

AJ Garber, MJ Abrahamson, JI Barzilay, L Blonde… - Endocrine practice, 2018 - Elsevier
ABSTRACT Abbreviations: A1C= hemoglobin A1C; AACE= American Association of Clinical
Endocrinologists; ACCORD= Action to Control Cardiovascular Risk in Diabetes; ACCORD …

The basis for weekly insulin therapy: evolving evidence with insulin icodec and insulin efsitora alfa

J Rosenstock, R Juneja, JM Beals, JS Moyers… - Endocrine …, 2024 - academic.oup.com
Basal insulin continues to be a vital part of therapy for many people with diabetes. First
attempts to prolong the duration of insulin formulations were through the development of …

A meta‐analysis comparing clinical effects of short‐or long‐acting GLP‐1 receptor agonists versus insulin treatment from head‐to‐head studies in type 2 diabetic …

MS Abd El Aziz, M Kahle, JJ Meier… - Diabetes, Obesity and …, 2017 - Wiley Online Library
Aims To study differences in clinical outcomes between initiating glucagon‐like peptide‐1
receptor agonist (GLP‐1 RAs) vs insulin treatment in patients with type 2 diabetes treated …

Type 2 diabetes mellitus in older people: a brief statement of key principles of modern day management including the assessment of frailty. A national collaborative …

WD Strain, SV Hope, A Green, P Kar… - Diabetic …, 2018 - Wiley Online Library
Rates of population ageing are unprecedented and this, combined with the progressive
urbanization of lifestyles, has led to a dramatic shift in the epidemiology of diabetes towards …

Hypoglycemia event rates: a comparison between real-world data and randomized controlled trial populations in insulin-treated diabetes

L Elliott, C Fidler, A Ditchfield, T Stissing - Diabetes Therapy, 2016 - Springer
Introduction Hypoglycemia is the most common adverse effect of diabetes therapy,
particularly insulin treatment. Hypoglycemia is associated with considerable clinical and …