Actions of prolactin in the brain: from physiological adaptations to stress and neurogenesis to psychopathology

L Torner - Frontiers in endocrinology, 2016 - frontiersin.org
Prolactin (PRL) is one of the most versatile hormones known. It is considered an adaptive
hormone due to the key roles it plays in the modulation of the stress response and during …

Prolactin function and putative expression in the brain

EA Cabrera-Reyes, O Limón-Morales… - Endocrine, 2017 - Springer
Introduction Prolactin is a peptide hormone mainly synthetized and secreted by the anterior
pituitary gland, but also by extrapituitary tissues, such as mammary gland, decidua, prostate …

Neuroendocrine regulation of lactation and milk production

WR Crowley - Comprehensive Physiology, 2011 - Wiley Online Library
Prolactin (PRL) released from lactotrophs of the anterior pituitary gland in response to the
suckling by the offspring is the major hormonal signal responsible for stimulation of milk …

The role of prolactin in central nervous system inflammation

E Ramos-Martinez, I Ramos-Martínez… - Reviews in the …, 2021 - degruyter.com
Prolactin has been shown to favor both the activation and suppression of the microglia and
astrocytes, as well as the release of inflammatory and anti-inflammatory cytokines. Prolactin …

Fluoride exposure induces inhibition of sodium/iodide symporter (NIS) contributing to impaired iodine absorption and iodine deficiency: molecular mechanisms of …

DT Waugh - International Journal of Environmental Research and …, 2019 - mdpi.com
The sodium iodide symporter (NIS) is the plasma membrane glycoprotein that mediates
active iodide transport in the thyroid and other tissues, such as the salivary, gastric mucosa …

Analysis of prolactin receptor expression in the murine brain using a novel prolactin receptor reporter mouse

IC Kokay, A Wyatt, HR Phillipps, M Aoki… - Journal of …, 2018 - Wiley Online Library
Prolactin influences a wide range of physiological functions via actions within the central
nervous system, as well as in peripheral tissues. A significant limitation in studies …

Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-κB activation

NA Rivero-Segura, E Flores-Soto… - PloS one, 2017 - journals.plos.org
Prolactin (PRL) is a peptidic hormone that displays pleiotropic functions in the organism
including different actions in the brain. PRL exerts a neuroprotective effect against …

Decoding signaling pathways involved in prolactin-induced neuroprotection: A review

G Molina-Salinas, NA Rivero-Segura… - Frontiers in …, 2021 - Elsevier
It has been well recognized that prolactin (PRL), a pleiotropic hormone, has many functions
in the brain, such as maternal behavior, neurogenesis, and neuronal plasticity, among …

Prolactin prevents mitochondrial dysfunction induced by glutamate excitotoxicity in hippocampal neurons

NA Rivero-Segura, MI Coronado-Mares… - Neuroscience …, 2019 - Elsevier
Prolactin (PRL) is a pleiotropic hormone secreted by several cells and tissues in the body,
such as mammary glands, T-lymphocytes, hypothalamus, among others. This hormone …

Hippocampal gene expression is highly responsive to estradiol replacement in middle-aged female rats

M Sárvári, I Kalló, E Hrabovszky, N Solymosi… - …, 2015 - academic.oup.com
In the hippocampus, estrogens are powerful modulators of neurotransmission, synaptic
plasticity and neurogenesis. In women, menopause is associated with increased risk of …