Protein lipidation: occurrence, mechanisms, biological functions, and enabling technologies
Protein lipidation, including cysteine prenylation, N-terminal glycine myristoylation, cysteine
palmitoylation, and serine and lysine fatty acylation, occurs in many proteins in eukaryotic …
palmitoylation, and serine and lysine fatty acylation, occurs in many proteins in eukaryotic …
Post-translational modifications of the protein termini
Post-translational modifications (PTM) involve enzyme-mediated covalent addition of
functional groups to proteins during or after synthesis. These modifications greatly increase …
functional groups to proteins during or after synthesis. These modifications greatly increase …
Comprehensive algorithm for quantitative real-time polymerase chain reaction
S Zhao, RD Fernald - Journal of computational biology, 2005 - liebertpub.com
Quantitative real-time polymerase chain reactions (qRT-PCR) have become the method of
choice for rapid, sensitive, quantitative comparison of RNA transcript abundance. Useful …
choice for rapid, sensitive, quantitative comparison of RNA transcript abundance. Useful …
[HTML][HTML] Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins
MD Resh - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 1999 - Elsevier
Covalent attachment of myristate and/or palmitate occurs on a wide variety of viral and
cellular proteins. This review will highlight the latest advances in our understanding of the …
cellular proteins. This review will highlight the latest advances in our understanding of the …
The biology and enzymology of proteinN-myristoylation* 210
Protein N-myristoylation refers to the covalent attachment of myristate, a 14-carbon saturated
fatty acid, to the N-terminal glycine of eukaryotic and viral proteins. N-Myristoylproteins have …
fatty acid, to the N-terminal glycine of eukaryotic and viral proteins. N-Myristoylproteins have …
N‐terminal modifications of cellular proteins: the enzymes involved, their substrate specificities and biological effects
The vast majority of eukaryotic proteins are N‐terminally modified by one or more
processing enzymes. Enzymes acting on the very first amino acid of a polypeptide include …
processing enzymes. Enzymes acting on the very first amino acid of a polypeptide include …
Protein myristoylation in health and disease
N-myristoylation is the attachment of a 14-carbon fatty acid, myristate, onto the N-terminal
glycine residue of target proteins, catalysed by N-myristoyltransferase (NMT), a ubiquitous …
glycine residue of target proteins, catalysed by N-myristoyltransferase (NMT), a ubiquitous …
N-terminal protein modifications: Bringing back into play the ribosome
C Giglione, S Fieulaine, T Meinnel - Biochimie, 2015 - Elsevier
N-terminal protein modifications correspond to the first modifications which in principle any
protein may undergo, before translation is completed by the ribosome. This class of …
protein may undergo, before translation is completed by the ribosome. This class of …
Eukaryotic fatty acylation drives plasma membrane targeting and enhances function of several type III effector proteins from Pseudomonas syringae
Z Nimchuk, E Marois, S Kjemtrup, RT Leister, F Katagiri… - Cell, 2000 - cell.com
Bacterial pathogens of plants and animals utilize conserved type III delivery systems to traffic
effector proteins into host cells. Plant innate immune systems evolved disease resistance (R) …
effector proteins into host cells. Plant innate immune systems evolved disease resistance (R) …
Epitope tagging
JW Jarvik, CA Telmer - Annual review of genetics, 1998 - annualreviews.org
▪ Abstract Epitope tagging is a recombinant DNA method by which a protein encoded by a
cloned gene is made immunoreactive to a known antibody. This review discusses the major …
cloned gene is made immunoreactive to a known antibody. This review discusses the major …