A series of novel 4-anilino quinazoline derivatives were taken based on the literature study
and optimized with Autodock version 4.2 and molecular dynamics (MD) protocol to …

Diseases characterized by out-of-control cell growth are known as cancer. One of the most
important mechanisms for handling it is the inhibition of the human topoisomerase II …

Management of the business-government relationship is critical for firm performance in
regulated industries. In this paper, we predict a U-shaped relationship between product …

In this work, we report a convenient method for the preparation of new 2-hydroxyethylamino-
substituted 6Н-1, 3, 4-thiadiazine hydrobromides for the search of new agents with …

Abstract Epidermal Growth Factor Receptor (EGFR) is a key player in cancer progression,
influencing critical signaling pathways such as Wnt/β-catenin, Transforming Growth Factor …

The objective of this work was to develop a Quantitative Structure Activity Relationship
(QSAR) model for understandingthe effect of topological polar surface area, lipo-affinity …

The objective of this work was to develop quantitative structure activity relationship (QSAR)
models from sulfonamide derivatives against anticonvulsant activity. For developing the …

Разработана модель количественного соотношения структура активность для
понимания влияния эксцентрического соединительного индекса, сложности …

A series of novel 4-anilino quinazoline derivatives were designed and optimized with
AutoDock 4.2 to investigate the interaction between the target compounds and the amino …

Diseases characterized by recurrent seizures are known as epilepsy. One of the most
important mechanisms for handling it is GABA 1 receptor mediated inhibition. In the same …