State of the art methods and challenges of luminescent metal–organic frameworks for antibiotic detection

R Yuan, H He - Inorganic Chemistry Frontiers, 2020 - pubs.rsc.org
Metal–organic frameworks (MOFs) are a burgeoning class of crystalline materials
constructed from metal cations/clusters and organic ligands with various potential …

Developing ciprofloxacin dry powder for inhalation: A story of challenges and rational design in the treatment of cystic fibrosis lung infection

N Alhajj, NJ O'Reilly, H Cathcart - International Journal of Pharmaceutics, 2022 - Elsevier
Cystic fibrosis (CF) is an inherited multisystem disease affecting the lung which leads to a
progressive decline in lung function as a result of malfunctioning mucociliary clearance and …

MOF-derived N-Co/Fe-PC composite as heterogeneous electro-Fenton catalysis combined with electrocoagulation process for enhanced degradation of Cu-CIP …

C Sun, J Wang, C Gu, C Wang, S Sun… - Chemical Engineering …, 2023 - Elsevier
Recently, heavy metal-antibiotic complexes have been frequently detected in wastewater,
posing a serious threat to the human health. In this study, a novel combination of …

Multi-targeted metallo-ciprofloxacin derivatives rationally designed and developed to overcome antimicrobial resistance

Z Ude, N Flothkötter, G Sheehan, M Brennan… - International Journal of …, 2021 - Elsevier
Antimicrobial resistance is a major global threat to human health due to the rise, spread and
persistence of multi-drug-resistant bacteria or 'superbugs'. There is an urgent need to …

[HTML][HTML] PK-PD Evaluation of Inhaled Microparticles loaded with Ciprofloxacin-Copper complex in a Rat Model of Chronic Pseudomonas aeruginosa Lung Infection.

F Tewes, B Lamy, J Laroche, I Lamarche… - International Journal of …, 2023 - Elsevier
The potential gain in efficacy of pulmonary administration over IV administration of some
antibiotics such as ciprofloxacin (CIP) may be limited by the short residence time of the drug …

The challenge of pulmonary Pseudomonas aeruginosa infection: How to bridge research and clinical pathology

OR Mendes - Viral, Parasitic, Bacterial, and Fungal Infections, 2023 - Elsevier
Pseudomonas aeruginosa (PA) is a gram-negative bacterium characterized by high
resistance to antibiotics. It is a major cause of nosocomial pulmonary infections, a …

[HTML][HTML] Recent Development of Fluoroquinolone Derivatives as Anticancer Agents

J Nowakowska, D Radomska, R Czarnomysy… - Molecules, 2024 - ncbi.nlm.nih.gov
Cancer is the second leading cause of death in the world following cardiovascular disease.
Its treatment, including radiation therapy and surgical removal of the tumour, is based on …

Inhalable tobramycin EEG powder formulation for treating Pseudomonas aeruginosa-induced lung infection

R Pangeni, S Poudel, MAM Momin, D Farkas… - International Journal of …, 2024 - Elsevier
Pulmonary delivery of antibiotics is an effective strategy in treating bacterial lung infection for
cystic fibrosis patients, by achieving high local drug concentrations and reducing overall …

[HTML][HTML] Comprehensive expectoration nursing in elderly patients with pulmonary infection and its influence on respiratory function

X Wu, H Zhang, J Chen - American Journal of Translational …, 2021 - ncbi.nlm.nih.gov
Objective: To investigate the effect of comprehensive expectoration nursing in elderly
patients with pulmonary infection and its influence on respiratory function. Methods: Clinical …